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    Ddn dendrin [ Mus musculus (house mouse) ]

    Gene ID: 13199, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ddnprovided by MGI
    Official Full Name
    dendrinprovided by MGI
    Primary source
    MGI:MGI:108101
    See related
    Ensembl:ENSMUSG00000059213 AllianceGenome:MGI:108101
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm748
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Located in nucleus and plasma membrane. Is expressed in glomerular tuft. Orthologous to human DDN (dendrin). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in frontal lobe adult (RPKM 210.2) and cortex adult (RPKM 198.8) See more
    Orthologs
    NEW
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    Genomic context

    See Ddn in Genome Data Viewer
    Location:
    15 F1; 15 54.69 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (98701663..98705806, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (98803782..98807925, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene wingless-type MMTV integration site family, member 10B Neighboring gene wingless-type MMTV integration site family, member 1 Neighboring gene protein kinase, AMP-activated, gamma 1 non-catalytic subunit Neighboring gene STARR-positive B cell enhancer ABC_E1918 Neighboring gene CapStarr-seq enhancer MGSCv37_chr15:98663163-98663346 Neighboring gene lysine (K)-specific methyltransferase 2D Neighboring gene STARR-seq mESC enhancer starr_39676

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cell projection ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in dendrite ISO
    Inferred from Sequence Orthology
    more info
     
    located_in dendritic spine membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in perikaryon IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in presynapse IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013741.1NP_001013763.1  dendrin

      See identical proteins and their annotated locations for NP_001013763.1

      Status: VALIDATED

      Source sequence(s)
      AK122363, AK158894
      Consensus CDS
      CCDS49723.1
      UniProtKB/Swiss-Prot
      Q3TPT2, Q3TY46, Q80TS7
      Related
      ENSMUSP00000074895.7, ENSMUST00000075444.8
      Conserved Domains (1) summary
      pfam15498
      Location:55708
      Dendrin; Nephrin and CD2AP-binding protein, Dendrin

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      98701663..98705806 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)