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    Zfp382 zinc finger protein 382 [ Mus musculus (house mouse) ]

    Gene ID: 233060, updated on 27-Nov-2024

    Summary

    Official Symbol
    Zfp382provided by MGI
    Official Full Name
    zinc finger protein 382provided by MGI
    Primary source
    MGI:MGI:3588204
    See related
    Ensembl:ENSMUSG00000074220 AllianceGenome:MGI:3588204
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    KS1; Znf382; 4930428B01Rik; 5930415A09Rik
    Summary
    Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human ZNF382 (zinc finger protein 382). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in CNS E18 (RPKM 2.8), testis adult (RPKM 2.3) and 24 other tissues See more
    Orthologs
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    Genomic context

    See Zfp382 in Genome Data Viewer
    Location:
    7; 7 B1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (29821255..29840180)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (30121833..30140758)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_18504 Neighboring gene zinc finger protein 566 Neighboring gene STARR-positive B cell enhancer ABC_E869 Neighboring gene zinc finger protein 260 Neighboring gene STARR-seq mESC enhancer starr_18505 Neighboring gene STARR-seq mESC enhancer starr_18508 Neighboring gene zinc finger protein 334 pseudogene Neighboring gene STARR-seq mESC enhancer starr_18509 Neighboring gene zinc finger protein 146

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    zinc finger protein 382
    Names
    KRAB/zinc finger suppressor protein 1
    multiple zinc finger and krueppel-associated box protein KS1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081007.2NP_001074476.1  zinc finger protein 382 isoform 1

      See identical proteins and their annotated locations for NP_001074476.1

      Status: VALIDATED

      Source sequence(s)
      AC164703
      Consensus CDS
      CCDS39877.1
      UniProtKB/Swiss-Prot
      B2RXC5, Q3UYY9
      Related
      ENSMUSP00000096196.4, ENSMUST00000098596.11
      Conserved Domains (6) summary
      smart00349
      Location:42102
      KRAB; krueppel associated box
      COG5048
      Location:411562
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:411431
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:523543
      zf-C2H2; Zinc finger, C2H2 type
      pfam01352
      Location:4281
      KRAB; KRAB box
      pfam13465
      Location:535560
      zf-H2C2_2; Zinc-finger double domain
    2. NM_001362158.1NP_001349087.1  zinc finger protein 382 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC164703
      Conserved Domains (3) summary
      smart00349
      Location:42102
      KRAB; krueppel associated box
      COG5048
      Location:410561
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:410430
      ZF_C2H2; C2H2 Zn finger [structural motif]
    3. NM_001362159.1NP_001349088.1  zinc finger protein 382 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC164703
      Conserved Domains (3) summary
      smart00349
      Location:1272
      KRAB; krueppel associated box
      COG5048
      Location:381532
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:381401
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      29821255..29840180
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017322166.3XP_017177655.1  zinc finger protein 382 isoform X1

      Conserved Domains (4) summary
      smart00349
      Location:1272
      KRAB; krueppel associated box
      COG5048
      Location:380531
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:380400
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:294316
      zf-C2H2; Zinc finger, C2H2 type