U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    adhP ethanol dehydrogenase/alcohol dehydrogenase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946036, updated on 17-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    adhP
    Official Full Name
    ethanol dehydrogenase/alcohol dehydrogenase
    Primary source
    ECOCYC:G6775
    Locus tag
    b1478
    See related
    ASAP:ABE-0004928
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1472; yddN
    Summary
    Medium chain dehydrogenase/reductase (MDR) activity reported by Shafqat (1999). [More information is available at EcoGene: EG12622]. AdhP is an ethanol-active medium-chain alcohol dehydrogenase/reductase. [More information is available at EcoCyc: G6775].
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (1552828..1553838, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene formate dehydrogenase N subunit beta Neighboring gene formate dehydrogenase N subunit gamma Neighboring gene DNA-binding transcriptional regulator YddM Neighboring gene malate dehydrogenase (oxaloacetate-decarboxylating) Neighboring gene ribosome-associated protein Sra

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Structure of Escherichia coli AdhP (ethanol-inducible dehydrogenase) with bound NAD. Thomas LM, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun, 2013 Jul. PMID 23832197, Free PMC Article
    2. Bacterial transposon Tn7 utilizes two different classes of target sites. Kubo KM, et al. J Bacteriol, 1990 May. PMID 2158980, Free PMC Article
    3. Temporal gene-expression in Escherichia coli K-12 biofilms. Domka J, et al. Environ Microbiol, 2007 Feb. PMID 17222132
    4. Over 1000 genes are involved in the DNA damage response of Escherichia coli. Khil PP, et al. Mol Microbiol, 2002 Apr. PMID 11967071
    5. Enzyme genomics: Application of general enzymatic screens to discover new enzymes. Kuznetsova E, et al. FEMS Microbiol Rev, 2005 Apr. PMID 15808744

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables alcohol dehydrogenase (NAD+) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables alcohol dehydrogenase (NAD+) activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables alcohol dehydrogenase (NAD+) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    NOT enables alcohol oxidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA damage response IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in acetaldehyde catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within acetaldehyde catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within response to ethanol IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    ethanol dehydrogenase/alcohol dehydrogenase
    NP_415995.4

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1552828..1553838 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415995.4 ethanol dehydrogenase/alcohol dehydrogenase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415995.4

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A6C9QFR6
      Conserved Domains (1) summary
      PRK09422
      Location:1 → 336
      PRK09422; ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.