cysM cysteine synthase B [Escherichia coli str. K-12 substr. MG1655] - Gene

Summary

Official Symbol: cysM
Official Full Name: cysteine synthase B
Primary source: ECOCYC:EG10193
Locus tag: b2421
See related: ASAP:ABE-0007982
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage: Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as: ECK2416
Summary: Cysteine synthase B is one of two isozymes in Escherichia coli that catalyze the formation of L-cysteine from O-acetyl-L-serine and sulfide . [More information is available at EcoCyc: EG10193].
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NC_000913.3 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

N-terminus verified by Edman degradation on complete protein
Title: Studies on the synthesis of the Fe-S cluster of dihydroxy-acid dehydratase in escherichia coli crude extract. Isolation of O-acetylserine sulfhydrylases A and B and beta-cystathionase based on their ability to mobilize sulfur from cysteine and to participate in Fe-S cluster synthesis.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables L-cysteine desulfhydrase activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables cysteine synthase activity	IBA Inferred from Biological aspect of Ancestor more info
enables cysteine synthase activity	IDA Inferred from Direct Assay more info	PubMed
enables cysteine synthase activity	IEA Inferred from Electronic Annotation more info
enables lyase activity	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein homodimerization activity	IDA Inferred from Direct Assay more info	PubMed
enables pyridoxal phosphate binding	IDA Inferred from Direct Assay more info	PubMed
enables transferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity, transferring alkyl or aryl (other than methyl) groups	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within L-cysteine catabolic process to pyruvate	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cysteine biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in cysteine biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cysteine biosynthetic process from serine	IDA Inferred from Direct Assay more info	PubMed
involved_in cysteine biosynthetic process from serine	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cysteine biosynthetic process via S-sulfo-L-cysteine	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within iron-sulfur cluster assembly	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

NP_416916.1

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