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    mcaS [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 2847751, updated on 3-Dec-2024

    Summary

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    Official Symbol
    mcaS
    Primary source
    ECOCYC:G0-8899
    Locus tag
    b4426
    See related
    ASAP:ABE-0047247
    Gene type
    ncRNA
    RNA name
    other
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1336; IS061; isrA
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    Genomic context

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    Sequence:
    NC_000913.3 (1405658..1405751, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene p-aminobenzoyl-glutamate hydrolase subunit B Neighboring gene p-aminobenzoyl-glutamate hydrolase subunit A Neighboring gene putative LysR-type DNA-binding transcriptional regulator AbgR Neighboring gene DNA endonuclease SmrA Neighboring gene diguanylate cyclase DgcM

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A small RNA that regulates motility and biofilm formation in response to changes in nutrient availability in Escherichia coli. Thomason MK, et al. Mol Microbiol, 2012 Apr. PMID 22289118, Free PMC Article
    2. sRNA-dependent control of curli biosynthesis in Escherichia coli: McaS directs endonucleolytic cleavage of csgD mRNA. Andreassen PR, et al. Nucleic Acids Res, 2018 Jul 27. PMID 29905843, Free PMC Article
    3. A bioinformatics based approach to discover small RNA genes in the Escherichia coli genome. Chen S, et al. Biosystems, 2002 Mar-May. PMID 12069726
    4. The small RNA regulators of Escherichia coli: roles and mechanisms*. Gottesman S. Annu Rev Microbiol, 2004. PMID 15487940
    5. An expanding universe of noncoding RNAs. Storz G. Science, 2002 May 17. PMID 12016301

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Endoribonucleolytic cleavage of csgD mRNA is the primary regulatory effect exerted by McaS.
      Title: sRNA-dependent control of curli biosynthesis in Escherichia coli: McaS directs endonucleolytic cleavage of csgD mRNA.
    2. An sRNA, IS061/IsrA, renamed McaS, represses CsgD expression and helps regulate the progression from a planktonic lifestyle to a sessile state in a biofilm.
      Title: A small RNA that regulates motility and biofilm formation in response to changes in nutrient availability in Escherichia coli.
    Submit: New GeneRIF Correction

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