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    glcA glycolate/lactate:H(+) symporter GlcA [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947259, updated on 3-Dec-2024

    Summary

    Official Symbol
    glcA
    Official Full Name
    glycolate/lactate:H(+) symporter GlcA
    Primary source
    ECOCYC:G7542
    Locus tag
    b2975
    See related
    ASAP:ABE-0009763
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2969; yghK
    Summary
    IT (Ion Transporter) superfamily (Prakash, 2003). [More information is available at EcoGene: EG12995]. YghK, also named GlcA, is a glycolate transporter that belongs to the Lactate Permease Family (LctP) , due to its strong sequence similarity with the L-lactate permease, LldP. [More information is available at EcoCyc: G7542].
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    Genomic context

    Sequence:
    NC_000913.3 (3119597..3121279, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene prepilin peptidase Neighboring gene putative lipoprotein YghJ Neighboring gene malate synthase G Neighboring gene putative heme-binding protein GlcG

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables glycolate transmembrane transporter activity EXP
    Inferred from Experiment
    more info
    PubMed 
    enables lactate transmembrane transporter activity EXP
    Inferred from Experiment
    more info
    PubMed 
    enables lactate transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables solute:proton symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables solute:proton symporter activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables symporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in glycolate transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within lactate transmembrane transport EXP
    Inferred from Experiment
    more info
    PubMed 
    involved_in lactate transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 

    General protein information

    Preferred Names
    glycolate/lactate:H(+) symporter GlcA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3119597..3121279 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417449.1 glycolate/lactate:H(+) symporter GlcA [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417449.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376M2J2, A0A8S7E8H4
      Conserved Domains (1) summary
      PRK09695
      Location:1560
      PRK09695; glycolate permease GlcA