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    PXN paxillin [ Homo sapiens (human) ]

    Gene ID: 5829, updated on 9-Dec-2024

    Summary

    Official Symbol
    PXNprovided by HGNC
    Official Full Name
    paxillinprovided by HGNC
    Primary source
    HGNC:HGNC:9718
    See related
    Ensembl:ENSG00000089159 MIM:602505; AllianceGenome:HGNC:9718
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    This gene encodes a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID:9054445). [provided by RefSeq, Aug 2011]
    Expression
    Ubiquitous expression in placenta (RPKM 24.8), fat (RPKM 20.4) and 25 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See PXN in Genome Data Viewer
    Location:
    12q24.23
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (120210447..120265730, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (120197626..120252894, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (120648250..120703533, complement)

    Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene GCN1 activator of EIF2AK4 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7132 Neighboring gene microRNA 4498 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr12:120622010-120623209 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4942 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:120635999-120636498 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:120636618-120637559 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7133 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7134 Neighboring gene Sharpr-MPRA regulatory region 12439 Neighboring gene PXN antisense RNA 1 Neighboring gene ribosomal protein lateral stalk subunit P0 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:120653807-120654533 Neighboring gene uncharacterized LOC124903034 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4943 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:120662858-120663539 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:120664223-120664903 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7135 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7136 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4944 Neighboring gene hESC enhancers GRCh37_chr12:120667255-120667814 and GRCh37_chr12:120667815-120668374 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr12:120668816-120670015 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:120670055-120670614 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:120671735-120672294 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:120676424-120677054 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:120682649-120683475 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7137 Neighboring gene ribosomal protein S20 pseudogene 31 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:120697989-120698555 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4945 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4946 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:120717966-120718466 Neighboring gene hESC enhancers GRCh37_chr12:120727716-120728708 and GRCh37_chr12:120728709-120729700 Neighboring gene NME2 pseudogene 1 Neighboring gene RNA, U4 small nuclear 2 Neighboring gene sirtuin 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    Related articles in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    HIV-1 interactions

    Protein interactions

    Protein Gene Interaction Pubs
    Envelope surface glycoprotein gp120 env SLIT2N, an active fragment of SLIT2, inhibits M-tropic HIV-1 gp120-induced Src signaling and activation of its downstream targets Pyk2, CDC42, Rac1, and paxillin in immature monocyte-derived dendritic cells PubMed
    Nef nef The Nef/hnRNPK/PKC-delta/Hck protein complex activates Pak2 activity but inhibits Pak1 activity, which induces paxillin phosphorylation on Ser272/274 and regulates paxillin/TACE association and secretion PubMed
    nef The Nef/hnRNPK/PKC-delta/Hck protein complex increases paxillin phosphorylation at Y118 and activates and secretes TACE through Erk1/2 activation PubMed
    Tat tat Endothelial cell adherent to HIV-1 Tat induces upregulation of VEGFR2, integrin beta(3) subunit, pp60src and recruits VEGFR2, integrin beta(3) subunit, paxillin, focal adhesion kinase, and pp60src to ventral plasma membranes PubMed
    tat HIV-1 Tat stimulates the phosphorylation of paxillin and its association with RAFTK, an effect linked to Tat-induced angiogenesis and AIDS-related Kaposi's sarcoma PubMed
    matrix gag HIV-1 MA co-localizes with beta2 integrin, alphaM and alphaX integrins in the intracellular thick electron-dense membrane compartments, which contain talin, vinculin and paxillin that connect the integrin complexes to the actin cytoskeleton PubMed

    Go to the HIV-1, Human Interaction Database

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ16691

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables beta-catenin binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables neuropilin binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein phosphatase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables vinculin binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cell cortex IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cell-cell junction IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
     
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    located_in focal adhesion HDA PubMed 
    located_in focal adhesion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in focal adhesion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    located_in lamellipodium IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of microtubule associated complex TAS
    Traceable Author Statement
    more info
    PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
     
    located_in stress fiber IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    paxillin
    Names
    testicular tissue protein Li 134

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_029820.1 RefSeqGene

      Range
      5042..60325
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001080855.3NP_001074324.1  paxillin isoform 2

      See identical proteins and their annotated locations for NP_001074324.1

      Status: REVIEWED

      Source sequence(s)
      BC144410, BU500419, BX648777, DB472926
      Consensus CDS
      CCDS44997.1
      UniProtKB/Swiss-Prot
      B2RAI3, B7ZMB4, O14970, O14971, O60360, P49023, Q5HYA4
      UniProtKB/TrEMBL
      A0A140VJQ8, B3KVL0
      Related
      ENSP00000228307.7, ENST00000228307.11
      Conserved Domains (5) summary
      cd09338
      Location:476528
      LIM3_Paxillin_like; The third LIM domain of the paxillin like protein family
      cd09407
      Location:417468
      LIM2_Paxillin; The second LIM domain of paxillin
      cd09411
      Location:535586
      LIM4_Paxillin; The fourth LIM domain of Paxillin
      cd09336
      Location:358410
      LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
      pfam03535
      Location:54253
      Paxillin; Paxillin family
    2. NM_001243756.2NP_001230685.1  paxillin isoform 3

      See identical proteins and their annotated locations for NP_001230685.1

      Status: REVIEWED

      Source sequence(s)
      AC004263
      Consensus CDS
      CCDS58281.1
      UniProtKB/TrEMBL
      B3KVL0
      Related
      ENSP00000267257.7, ENST00000267257.11
      Conserved Domains (5) summary
      cd09338
      Location:490542
      LIM3_Paxillin_like; The third LIM domain of the paxillin like protein family
      cd09407
      Location:431482
      LIM2_Paxillin; The second LIM domain of paxillin
      cd09411
      Location:549600
      LIM4_Paxillin; The fourth LIM domain of Paxillin
      cd09336
      Location:372424
      LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
      pfam03535
      Location:54253
      Paxillin; Paxillin family
    3. NM_001385981.1NP_001372910.1  paxillin isoform 5

      Status: REVIEWED

      Source sequence(s)
      AC004263
      Consensus CDS
      CCDS91759.1
      UniProtKB/TrEMBL
      A0A1B0GTU4
      Related
      ENSP00000489840.1, ENST00000637617.2
      Conserved Domains (6) summary
      cd09338
      Location:9661018
      LIM3_Paxillin_like; The third LIM domain of the paxillin like protein family
      cd09407
      Location:907958
      LIM2_Paxillin; The second LIM domain of paxillin
      cd09411
      Location:10251076
      LIM4_Paxillin; The fourth LIM domain of Paxillin
      PHA03247
      Location:314606
      PHA03247; large tegument protein UL36; Provisional
      cd09336
      Location:848900
      LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
      pfam03535
      Location:54253
      Paxillin; Paxillin family
    4. NM_001385982.1NP_001372911.1  paxillin isoform 6

      Status: REVIEWED

      Source sequence(s)
      AC004263
      Conserved Domains (5) summary
      cd09338
      Location:874926
      LIM3_Paxillin_like; The third LIM domain of the paxillin like protein family
      cd09407
      Location:815866
      LIM2_Paxillin; The second LIM domain of paxillin
      cd09411
      Location:933984
      LIM4_Paxillin; The fourth LIM domain of Paxillin
      cd09336
      Location:756808
      LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
      pfam03535
      Location:54253
      Paxillin; Paxillin family
    5. NM_001385983.1NP_001372912.1  paxillin isoform 7

      Status: REVIEWED

      Source sequence(s)
      AC004263
      Conserved Domains (5) summary
      cd09338
      Location:872924
      LIM3_Paxillin_like; The third LIM domain of the paxillin like protein family
      cd09407
      Location:813864
      LIM2_Paxillin; The second LIM domain of paxillin
      cd09411
      Location:931982
      LIM4_Paxillin; The fourth LIM domain of Paxillin
      cd09336
      Location:754806
      LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
      pfam03535
      Location:54253
      Paxillin; Paxillin family
    6. NM_001385984.1NP_001372913.1  paxillin isoform 8

      Status: REVIEWED

      Source sequence(s)
      AC004263
      Conserved Domains (6) summary
      cd09338
      Location:785837
      LIM3_Paxillin_like; The third LIM domain of the paxillin like protein family
      cd09407
      Location:726777
      LIM2_Paxillin; The second LIM domain of paxillin
      cd09411
      Location:844895
      LIM4_Paxillin; The fourth LIM domain of Paxillin
      PHA03247
      Location:314553
      PHA03247; large tegument protein UL36; Provisional
      cd09336
      Location:667719
      LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
      pfam03535
      Location:54253
      Paxillin; Paxillin family
    7. NM_001385985.1NP_001372914.1  paxillin isoform 9

      Status: REVIEWED

      Source sequence(s)
      AC004263
      Conserved Domains (6) summary
      cd09338
      Location:737789
      LIM3_Paxillin_like; The third LIM domain of the paxillin like protein family
      cd09407
      Location:678729
      LIM2_Paxillin; The second LIM domain of paxillin
      cd09411
      Location:796847
      LIM4_Paxillin; The fourth LIM domain of Paxillin
      PHA03247
      Location:314553
      PHA03247; large tegument protein UL36; Provisional
      cd09336
      Location:619671
      LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
      pfam03535
      Location:54253
      Paxillin; Paxillin family
    8. NM_001385986.1NP_001372915.1  paxillin isoform 10

      Status: REVIEWED

      Source sequence(s)
      AC004263
      Conserved Domains (6) summary
      cd09338
      Location:625677
      LIM3_Paxillin_like; The third LIM domain of the paxillin like protein family
      cd09407
      Location:566617
      LIM2_Paxillin; The second LIM domain of paxillin
      cd09411
      Location:684735
      LIM4_Paxillin; The fourth LIM domain of Paxillin
      PHA03307
      Location:91459
      PHA03307; transcriptional regulator ICP4; Provisional
      cd09336
      Location:507559
      LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
      pfam03535
      Location:54253
      Paxillin; Paxillin family
    9. NM_001385987.1NP_001372916.1  paxillin isoform 11

      Status: REVIEWED

      Source sequence(s)
      AC004263
      UniProtKB/TrEMBL
      B3KVL0
      Conserved Domains (5) summary
      cd09338
      Location:579631
      LIM3_Paxillin_like; The third LIM domain of the paxillin like protein family
      cd09407
      Location:520571
      LIM2_Paxillin; The second LIM domain of paxillin
      cd09411
      Location:638689
      LIM4_Paxillin; The fourth LIM domain of Paxillin
      cd09336
      Location:461513
      LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
      pfam03535
      Location:54253
      Paxillin; Paxillin family
    10. NM_001385988.1NP_001372917.1  paxillin isoform 12

      Status: REVIEWED

      Source sequence(s)
      AC004263
      UniProtKB/TrEMBL
      B3KVL0
      Conserved Domains (4) summary
      cd09407
      Location:465516
      LIM2_Paxillin; The second LIM domain of paxillin
      cd09336
      Location:406458
      LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
      pfam03535
      Location:54253
      Paxillin; Paxillin family
      cl02475
      Location:524550
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    11. NM_001385989.1NP_001372918.1  paxillin isoform 13

      Status: REVIEWED

      Source sequence(s)
      AC004263
      UniProtKB/TrEMBL
      B3KVL0
      Conserved Domains (4) summary
      cd09407
      Location:415466
      LIM2_Paxillin; The second LIM domain of paxillin
      cd09336
      Location:356408
      LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
      pfam03535
      Location:54253
      Paxillin; Paxillin family
      cl02475
      Location:474500
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    12. NM_001385990.1NP_001372919.1  paxillin isoform 14

      Status: REVIEWED

      Source sequence(s)
      AC004263
      Conserved Domains (4) summary
      cd09407
      Location:383434
      LIM2_Paxillin; The second LIM domain of paxillin
      cd09336
      Location:324376
      LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
      pfam03535
      Location:54253
      Paxillin; Paxillin family
      cl02475
      Location:442468
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    13. NM_001410986.1NP_001397915.1  paxillin isoform 15

      Status: REVIEWED

      Source sequence(s)
      AC004263
      Consensus CDS
      CCDS91758.1
      UniProtKB/TrEMBL
      B3KVL0, F5GZ78
      Related
      ENSP00000443887.1, ENST00000536957.5
    14. NM_002859.4NP_002850.2  paxillin isoform 1

      See identical proteins and their annotated locations for NP_002850.2

      Status: REVIEWED

      Source sequence(s)
      BC136794, BC144410, BU500419, BX648777, DB472926
      Consensus CDS
      CCDS44996.1
      UniProtKB/TrEMBL
      B3KVL0
      Related
      ENSP00000391283.2, ENST00000424649.6
      Conserved Domains (5) summary
      cd09338
      Location:442494
      LIM3_Paxillin_like; The third LIM domain of the paxillin like protein family
      cd09407
      Location:383434
      LIM2_Paxillin; The second LIM domain of paxillin
      cd09411
      Location:501552
      LIM4_Paxillin; The fourth LIM domain of Paxillin
      cd09336
      Location:324376
      LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
      pfam03535
      Location:54253
      Paxillin; Paxillin family
    15. NM_025157.5NP_079433.3  paxillin isoform 4

      See identical proteins and their annotated locations for NP_079433.3

      Status: REVIEWED

      Source sequence(s)
      AC004263, BC136794, BC144410, BU500419, BX648777, DA565031
      Consensus CDS
      CCDS44998.1
      UniProtKB/Swiss-Prot
      P49023
      Related
      ENSP00000395536.2, ENST00000458477.6
      Conserved Domains (4) summary
      cd09338
      Location:309361
      LIM3_Paxillin_like; The third LIM domain of the paxillin like protein family
      cd09336
      Location:191243
      LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
      cl02475
      Location:250301
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
      pfam03535
      Location:1120
      Paxillin; Paxillin family

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

      Range
      120210447..120265730 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047429246.1XP_047285202.1  paxillin isoform X15

      UniProtKB/TrEMBL
      B3KVL0
    2. XM_047429241.1XP_047285197.1  paxillin isoform X9

      UniProtKB/TrEMBL
      B3KVL0
    3. XM_047429240.1XP_047285196.1  paxillin isoform X8

      UniProtKB/TrEMBL
      B3KVL0
    4. XM_047429239.1XP_047285195.1  paxillin isoform X7

    5. XM_006719532.3XP_006719595.1  paxillin isoform X2

      Conserved Domains (5) summary
      cd09338
      Location:10141066
      LIM3_Paxillin_like; The third LIM domain of the paxillin like protein family
      cd09407
      Location:9551006
      LIM2_Paxillin; The second LIM domain of paxillin
      cd09411
      Location:10731124
      LIM4_Paxillin; The fourth LIM domain of Paxillin
      cd09336
      Location:896948
      LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
      pfam03535
      Location:54253
      Paxillin; Paxillin family
    6. XM_011538622.2XP_011536924.1  paxillin isoform X3

      See identical proteins and their annotated locations for XP_011536924.1

      Conserved Domains (5) summary
      cd09338
      Location:881933
      LIM3_Paxillin_like; The third LIM domain of the paxillin like protein family
      cd09407
      Location:822873
      LIM2_Paxillin; The second LIM domain of paxillin
      cd09411
      Location:940991
      LIM4_Paxillin; The fourth LIM domain of Paxillin
      cd09336
      Location:763815
      LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
      pfam03535
      Location:1120
      Paxillin; Paxillin family
    7. XM_047429236.1XP_047285192.1  paxillin isoform X1

    8. XM_047429250.1XP_047285206.1  paxillin isoform X19

      UniProtKB/TrEMBL
      B3KVL0
    9. XM_047429243.1XP_047285199.1  paxillin isoform X12

      UniProtKB/TrEMBL
      B3KVL0
    10. XM_047429249.1XP_047285205.1  paxillin isoform X18

      UniProtKB/TrEMBL
      B3KVL0
    11. XM_047429242.1XP_047285198.1  paxillin isoform X11

      UniProtKB/TrEMBL
      B3KVL0
    12. XM_047429244.1XP_047285200.1  paxillin isoform X14

      UniProtKB/TrEMBL
      B3KVL0
    13. XM_017019742.3XP_016875231.1  paxillin isoform X17

      UniProtKB/TrEMBL
      B3KVL0
      Conserved Domains (5) summary
      cd09338
      Location:448500
      LIM3_Paxillin_like; The third LIM domain of the paxillin like protein family
      cd09407
      Location:389440
      LIM2_Paxillin; The second LIM domain of paxillin
      cd09411
      Location:507558
      LIM4_Paxillin; The fourth LIM domain of Paxillin
      cd09336
      Location:330382
      LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
      pfam03535
      Location:60259
      Paxillin; Paxillin family
    14. XM_017019739.3XP_016875228.1  paxillin isoform X10

      UniProtKB/TrEMBL
      B3KVL0
      Conserved Domains (5) summary
      cd09338
      Location:496548
      LIM3_Paxillin_like; The third LIM domain of the paxillin like protein family
      cd09407
      Location:437488
      LIM2_Paxillin; The second LIM domain of paxillin
      cd09411
      Location:555606
      LIM4_Paxillin; The fourth LIM domain of Paxillin
      cd09336
      Location:378430
      LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
      pfam03535
      Location:60259
      Paxillin; Paxillin family
    15. XM_017019740.3XP_016875229.1  paxillin isoform X13

      UniProtKB/TrEMBL
      B3KVL0
      Conserved Domains (5) summary
      cd09338
      Location:482534
      LIM3_Paxillin_like; The third LIM domain of the paxillin like protein family
      cd09407
      Location:423474
      LIM2_Paxillin; The second LIM domain of paxillin
      cd09411
      Location:541592
      LIM4_Paxillin; The fourth LIM domain of Paxillin
      cd09336
      Location:364416
      LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
      pfam03535
      Location:60259
      Paxillin; Paxillin family
    16. XM_047429252.1XP_047285208.1  paxillin isoform X21

    17. XM_047429253.1XP_047285209.1  paxillin isoform X22

    18. XM_047429251.1XP_047285207.1  paxillin isoform X20

    19. XM_047429238.1XP_047285194.1  paxillin isoform X6

    20. XM_047429237.1XP_047285193.1  paxillin isoform X5

    21. XM_047429248.1XP_047285204.1  paxillin isoform X16

    22. XM_017019732.3XP_016875221.2  paxillin isoform X4

    RNA

    1. XR_002957365.2 RNA Sequence

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060936.1 Alternate T2T-CHM13v2.0

      Range
      120197626..120252894 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054372755.1XP_054228730.1  paxillin isoform X15

      UniProtKB/TrEMBL
      B3KVL0
    2. XM_054372748.1XP_054228723.1  paxillin isoform X9

      UniProtKB/TrEMBL
      B3KVL0
    3. XM_054372747.1XP_054228722.1  paxillin isoform X8

      UniProtKB/TrEMBL
      B3KVL0
    4. XM_054372741.1XP_054228716.1  paxillin isoform X7

    5. XM_054372732.1XP_054228707.1  paxillin isoform X2

    6. XM_054372735.1XP_054228710.1  paxillin isoform X3

    7. XM_054372730.1XP_054228705.1  paxillin isoform X1

    8. XM_054372758.1XP_054228733.1  paxillin isoform X19

      UniProtKB/TrEMBL
      B3KVL0
    9. XM_054372751.1XP_054228726.1  paxillin isoform X12

      UniProtKB/TrEMBL
      B3KVL0
    10. XM_054372733.1XP_054228708.1  paxillin isoform X24

    11. XM_054372757.1XP_054228732.1  paxillin isoform X18

      UniProtKB/TrEMBL
      B3KVL0
    12. XM_054372750.1XP_054228725.1  paxillin isoform X11

      UniProtKB/TrEMBL
      B3KVL0
    13. XM_054372754.1XP_054228729.1  paxillin isoform X14

      UniProtKB/TrEMBL
      B3KVL0
    14. XM_054372746.1XP_054228721.1  paxillin isoform X35

      UniProtKB/TrEMBL
      B3KVL0
    15. XM_054372743.1XP_054228718.1  paxillin isoform X32

      UniProtKB/TrEMBL
      B3KVL0
    16. XM_054372731.1XP_054228706.1  paxillin isoform X23

    17. XM_054372756.1XP_054228731.1  paxillin isoform X17

      UniProtKB/TrEMBL
      B3KVL0
    18. XM_054372749.1XP_054228724.1  paxillin isoform X10

      UniProtKB/TrEMBL
      B3KVL0
    19. XM_054372753.1XP_054228728.1  paxillin isoform X36

      UniProtKB/TrEMBL
      B3KVL0
    20. XM_054372745.1XP_054228720.1  paxillin isoform X34

      UniProtKB/TrEMBL
      B3KVL0
    21. XM_054372752.1XP_054228727.1  paxillin isoform X13

      UniProtKB/TrEMBL
      B3KVL0
    22. XM_054372744.1XP_054228719.1  paxillin isoform X33

      UniProtKB/TrEMBL
      B3KVL0
    23. XM_054372742.1XP_054228717.1  paxillin isoform X31

      UniProtKB/TrEMBL
      B3KVL0
    24. XM_054372740.1XP_054228715.1  paxillin isoform X30

    25. XM_054372739.1XP_054228714.1  paxillin isoform X29

    26. XM_054372738.1XP_054228713.1  paxillin isoform X28

    27. XM_054372737.1XP_054228712.1  paxillin isoform X27

    28. XM_054372734.1XP_054228709.1  paxillin isoform X25

    29. XM_054372736.1XP_054228711.1  paxillin isoform X26

    RNA

    1. XR_008488651.1 RNA Sequence