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    OR4F6 olfactory receptor family 4 subfamily F member 6 [ Homo sapiens (human) ]

    Gene ID: 390648, updated on 27-Nov-2024

    Summary

    Official Symbol
    OR4F6provided by HGNC
    Official Full Name
    olfactory receptor family 4 subfamily F member 6provided by HGNC
    Primary source
    HGNC:HGNC:15372
    See related
    Ensembl:ENSG00000184140 AllianceGenome:HGNC:15372
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    OR4F12; OR15-15
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
    Orthologs
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    Genomic context

    See OR4F6 in Genome Data Viewer
    Location:
    15q26.3
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (101803509..101806887)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (99570010..99573387)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (102343712..102347090)

    Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene RNA, 7SL, cytoplasmic 209, pseudogene Neighboring gene golgin A8 family member V, pseudogene Neighboring gene olfactory receptor family 4 subfamily F member 15 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr15:102368999-102370198 Neighboring gene olfactory receptor family 4 subfamily F member 14 pseudogene

    Genomic regions, transcripts, and products

    General protein information

    Preferred Names
    olfactory receptor 4F6
    Names
    olfactory receptor 4F12
    olfactory receptor OR15-15
    olfactory receptor, family 4, subfamily F, member 12

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001005326.2NP_001005326.1  olfactory receptor 4F6

      See identical proteins and their annotated locations for NP_001005326.1

      Status: VALIDATED

      Source sequence(s)
      AC107977
      Consensus CDS
      CCDS32341.1
      UniProtKB/Swiss-Prot
      B9EH28, Q6IF95, Q8NGB9
      UniProtKB/TrEMBL
      A0A126GV96
      Related
      ENSP00000327525.4, ENST00000328882.6
      Conserved Domains (2) summary
      pfam00001
      Location:41287
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:32300
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

      Range
      101803509..101806887
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060939.1 Alternate T2T-CHM13v2.0

      Range
      99570010..99573387
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)