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    Fam135b family with sequence similarity 135, member B [ Mus musculus (house mouse) ]

    Gene ID: 70363, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Fam135bprovided by MGI
    Official Full Name
    family with sequence similarity 135, member Bprovided by MGI
    Primary source
    MGI:MGI:1917613
    See related
    Ensembl:ENSMUSG00000036800 AllianceGenome:MGI:1917613
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700010C24Rik; A830008O07Rik
    Summary
    Predicted to be involved in cellular lipid metabolic process. Is expressed in medulla oblongata; spinal cord; and ventral grey horn. Orthologous to human FAM135B (family with sequence similarity 135 member B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in cerebellum adult (RPKM 2.5), cortex adult (RPKM 2.0) and 5 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Fam135b in Genome Data Viewer
    Location:
    15 D3; 15 32.19 cM
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (71310800..71600282, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (71438951..71728434, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene FCF1 small subunit processome component homolog pseudogene Neighboring gene prune homolog pseudogene Neighboring gene STARR-seq mESC enhancer starr_38922 Neighboring gene STARR-positive B cell enhancer mm9_chr15:71568232-71568532 Neighboring gene STARR-seq mESC enhancer starr_38923 Neighboring gene predicted gene, 22519 Neighboring gene eukaryotic translation initiation factor 4A2 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC159348, MGC159350

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in lipid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    protein FAM135B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177819.3 → NP_808487.2  protein FAM135B

      See identical proteins and their annotated locations for NP_808487.2

      Status: VALIDATED

      Source sequence(s)
      AC125528, AC157277, AC157602, AK005816, BC119174
      Consensus CDS
      CCDS49626.1
      UniProtKB/Swiss-Prot
      Q9DAI6
      Related
      ENSMUSP00000022953.9, ENSMUST00000022953.10
      Conserved Domains (2) summary
      pfam05057
      Location:1133 → 1327
      DUF676; Putative serine esterase (DUF676)
      pfam12394
      Location:111 → 170
      DUF3657; Protein FAM135

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      71310800..71600282 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006521393.4 → XP_006521456.1  protein FAM135B isoform X1

      See identical proteins and their annotated locations for XP_006521456.1

      UniProtKB/Swiss-Prot
      Q9DAI6
      Conserved Domains (2) summary
      pfam05057
      Location:1133 → 1327
      DUF676; Putative serine esterase (DUF676)
      pfam12394
      Location:111 → 170
      DUF3657; Protein FAM135

    2. XM_006521395.4 → XP_006521458.1  protein FAM135B isoform X1

      See identical proteins and their annotated locations for XP_006521458.1

      UniProtKB/Swiss-Prot
      Q9DAI6
      Conserved Domains (2) summary
      pfam05057
      Location:1133 → 1327
      DUF676; Putative serine esterase (DUF676)
      pfam12394
      Location:111 → 170
      DUF3657; Protein FAM135

    RNA

    1. XR_003951438.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9DAI6.3 GenPept UniProtKB/Swiss-Prot:Q9DAI6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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