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    Cep295nl CEP295 N-terminal like [ Mus musculus (house mouse) ]

    Gene ID: 58251, updated on 27-Nov-2024

    Summary

    Official Symbol
    Cep295nlprovided by MGI
    Official Full Name
    CEP295 N-terminal likeprovided by MGI
    Primary source
    MGI:MGI:1929713
    See related
    Ensembl:ENSMUSG00000076433 AllianceGenome:MGI:1929713
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ddc8; FS39; Kiaa1731nl
    Summary
    Predicted to enable microtubule binding activity. Predicted to be involved in regulation of centriole replication. Located in motile cilium. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; retina; and spleen. Orthologous to human CEP295NL (CEP295 N-terminal like). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward testis adult (RPKM 85.2) See more
    Orthologs
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    Genomic context

    See Cep295nl in Genome Data Viewer
    Location:
    11 E2; 11 83.09 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (118223186..118233368, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (118332360..118342542, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene cytohesin 1 Neighboring gene STARR-positive B cell enhancer ABC_E7106 Neighboring gene STARR-positive B cell enhancer ABC_E9850 Neighboring gene VISTA enhancer mm1622 Neighboring gene STARR-positive B cell enhancer ABC_E5309 Neighboring gene STARR-positive B cell enhancer mm9_chr11:118109942-118110243 Neighboring gene STARR-positive B cell enhancer ABC_E9851 Neighboring gene ubiquitin specific peptidase 36 Neighboring gene STARR-positive B cell enhancer ABC_E1852 Neighboring gene STARR-seq mESC enhancer starr_31299 Neighboring gene tissue inhibitor of metalloproteinase 2 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:118209837-118210038 Neighboring gene STARR-seq mESC enhancer starr_31301 Neighboring gene lectin, galactoside-binding, soluble, 3 binding protein Neighboring gene STARR-positive B cell enhancer ABC_E5311 Neighboring gene calcium activated nucleotidase 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in regulation of centriole replication IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in centriole IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in motile cilium IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    CEP295 N-terminal-like protein
    Names
    KIAA1731 N-terminal like protein
    differential display clone 8
    protein DDC8
    testis specific protein, Ddc8
    testis-specific protein DDC8

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_021440.2NP_067415.2  CEP295 N-terminal-like protein

      See identical proteins and their annotated locations for NP_067415.2

      Status: VALIDATED

      Source sequence(s)
      AK132657, BC100451, BX520604
      Consensus CDS
      CCDS25700.1
      UniProtKB/Swiss-Prot
      P97320, Q497N6
      Related
      ENSMUSP00000099313.4, ENSMUST00000103024.4

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      118223186..118233368 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011249166.3XP_011247468.1  CEP295 N-terminal-like protein isoform X2

      See identical proteins and their annotated locations for XP_011247468.1

      UniProtKB/Swiss-Prot
      P97320, Q497N6
      Related
      ENSMUSP00000128122.2, ENSMUST00000168100.3
    2. XM_006533859.4XP_006533922.1  CEP295 N-terminal-like protein isoform X1