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    Basp1 brain abundant, membrane attached signal protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 70350, updated on 9-Dec-2024

    Summary

    Official Symbol
    Basp1provided by MGI
    Official Full Name
    brain abundant, membrane attached signal protein 1provided by MGI
    Primary source
    MGI:MGI:1917600
    See related
    Ensembl:ENSMUSG00000045763 AllianceGenome:MGI:1917600
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CAP23; Ckap3; NAP22; CAP-23; NAP-22; 2610024P12Rik
    Summary
    Enables transcription cis-regulatory region binding activity. Involved in podocyte differentiation. Located in chromatin; cytoplasm; and nuclear speck. Is expressed in limb; nervous system; and neural ectoderm. Orthologous to human BASP1 (brain abundant membrane attached signal protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in CNS E18 (RPKM 284.7), CNS E14 (RPKM 216.7) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Basp1 in Genome Data Viewer
    Location:
    15 B1; 15 9.16 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (25363363..25413850, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (25363277..25413764, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_38159 Neighboring gene predicted gene, 35996 Neighboring gene STARR-seq mESC enhancer starr_38160 Neighboring gene STARR-seq mESC enhancer starr_38161 Neighboring gene STARR-positive B cell enhancer ABC_E5470 Neighboring gene RIKEN cDNA 4930445E18 gene Neighboring gene STARR-seq mESC enhancer starr_38162 Neighboring gene STARR-seq mESC enhancer starr_38163 Neighboring gene STARR-seq mESC enhancer starr_38164 Neighboring gene predicted gene, 36555 Neighboring gene predicted gene 5468 Neighboring gene STARR-seq mESC enhancer starr_38167 Neighboring gene STARR-seq mESC enhancer starr_38168 Neighboring gene predicted gene, 36642

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Targeted (4)  1 citation

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables calmodulin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein domain specific binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein domain specific binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables transcription cis-regulatory region binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables transcription cis-regulatory region binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables transcription corepressor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables transcription corepressor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables transcription corepressor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in negative regulation of DNA-templated transcription ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in podocyte differentiation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in protein homooligomerization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein homooligomerization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in supramolecular fiber organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in supramolecular fiber organization ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of COP9 signalosome IEA
    Inferred from Electronic Annotation
    more info
     
    part_of COP9 signalosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in PML body IEA
    Inferred from Electronic Annotation
    more info
     
    located_in PML body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cell junction ISO
    Inferred from Sequence Orthology
    more info
     
    located_in chromatin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in growth cone IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nuclear matrix IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nuclear matrix ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear speck IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    brain acid soluble protein 1
    Names
    22 kDa neuronal tissue-enriched acidic protein
    cytoskeleton associated protein 3
    neuronal axonal membrane protein NAP-22

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027395.2NP_081671.1  brain acid soluble protein 1

      See identical proteins and their annotated locations for NP_081671.1

      Status: VALIDATED

      Source sequence(s)
      AC161537
      Consensus CDS
      CCDS27398.1
      UniProtKB/Swiss-Prot
      Q91XV3
      Related
      ENSMUSP00000053943.8, ENSMUST00000058845.9
      Conserved Domains (1) summary
      pfam05466
      Location:12183
      BASP1; Brain acid soluble protein 1 (BASP1 protein)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      25363363..25413850 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)