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    Orm2 orosomucoid 2 [ Mus musculus (house mouse) ]

    Gene ID: 18406, updated on 9-Dec-2024

    Summary

    Official Symbol
    Orm2provided by MGI
    Official Full Name
    orosomucoid 2provided by MGI
    Primary source
    MGI:MGI:97444
    See related
    Ensembl:ENSMUSG00000061540 AllianceGenome:MGI:97444
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Agp1; Orm-2
    Summary
    Predicted to enable small molecule binding activity. Predicted to be involved in acute-phase response and regulation of immune system process. Predicted to be active in extracellular space. Orthologous to several human genes including ORM2 (orosomucoid 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in liver adult (RPKM 37.5), subcutaneous fat pad adult (RPKM 8.0) and 2 other tissues See more
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    Genomic context

    See Orm2 in Genome Data Viewer
    Location:
    4 B3; 4 33.96 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (63280543..63284114)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (63362449..63365877)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene orosomucoid 1 pseudogene Neighboring gene orosomucoid 3 Neighboring gene AT-hook transcription factor Neighboring gene AT-hook transcription factor, opposite strand Neighboring gene predicted gene, 52742

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (4)  1 citation
    • Targeted (1) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables small molecule binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in acute-phase response IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of immune system process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
     
    located_in extracellular space ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    alpha-1-acid glycoprotein 2
    Names
    AGP 2
    OMD 2
    bM340H1.5 (orosomucoid 2)

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011016.2NP_035146.1  alpha-1-acid glycoprotein 2 precursor

      See identical proteins and their annotated locations for NP_035146.1

      Status: VALIDATED

      Source sequence(s)
      CB949119, M27009
      Consensus CDS
      CCDS18253.1
      UniProtKB/Swiss-Prot
      P07361
      Related
      ENSMUSP00000074810.4, ENSMUST00000075341.4
      Conserved Domains (1) summary
      pfam00061
      Location:43181
      Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      63280543..63284114
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036163821.1XP_036019714.1  alpha-1-acid glycoprotein 2 isoform X1

      Conserved Domains (1) summary
      cl10502
      Location:21145
      lipocalin_FABP; lipocalin/cytosolic fatty acid-binding protein family