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    Shisa3 shisa family member 3 [ Mus musculus (house mouse) ]

    Gene ID: 330096, updated on 9-Dec-2024

    Summary

    Official Symbol
    Shisa3provided by MGI
    Official Full Name
    shisa family member 3provided by MGI
    Primary source
    MGI:MGI:3041225
    See related
    Ensembl:ENSMUSG00000050010 AllianceGenome:MGI:3041225
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    D830007B15Rik
    Summary
    Acts upstream of or within negative regulation of canonical Wnt signaling pathway. Predicted to be located in endoplasmic reticulum membrane. Is expressed in several structures, including brain; cranium; embryo mesenchyme; future brain; and gut. Orthologous to human SHISA3 (shisa family member 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in testis adult (RPKM 11.0), frontal lobe adult (RPKM 5.2) and 14 other tissues See more
    Orthologs
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    Genomic context

    See Shisa3 in Genome Data Viewer
    Location:
    5 C3.1; 5 36.15 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (67765226..67771330)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (67607883..67613987)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA C330024D21 gene Neighboring gene CRISPRi-validated cis-regulatory element for Bend4 and Bendr Neighboring gene predicted gene, 40315 Neighboring gene 60S ribosomal protein L37 pseudogene Neighboring gene STARR-seq mESC enhancer starr_13319 Neighboring gene STARR-seq mESC enhancer starr_13320 Neighboring gene STARR-seq mESC enhancer starr_13321 Neighboring gene ATPase phospholipid transporting 8A1 Neighboring gene predicted gene 15478 Neighboring gene predicted gene, 46914

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General protein information

    Preferred Names
    protein shisa-3 homolog
    Names
    shisa homolog 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033415.3NP_001028587.1  protein shisa-3 homolog precursor

      See identical proteins and their annotated locations for NP_001028587.1

      Status: VALIDATED

      Source sequence(s)
      AC123662, AK143290
      Consensus CDS
      CCDS19318.1
      UniProtKB/Swiss-Prot
      Q3UPR0, Q8C5V3
      Related
      ENSMUSP00000084494.6, ENSMUST00000087241.7
      Conserved Domains (1) summary
      pfam13908
      Location:25161
      Shisa; Wnt and FGF inhibitory regulator

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      67765226..67771330
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)