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    Mrps25 mitochondrial ribosomal protein S25 [ Mus musculus (house mouse) ]

    Gene ID: 64658, updated on 9-Dec-2024

    Summary

    Official Symbol
    Mrps25provided by MGI
    Official Full Name
    mitochondrial ribosomal protein S25provided by MGI
    Primary source
    MGI:MGI:1928140
    See related
    Ensembl:ENSMUSG00000014551 AllianceGenome:MGI:1928140
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rpms25; 2810429N01Rik
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to act upstream of or within mitochondrial translation. Located in mitochondrion. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and immune system. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 50. Orthologous to human MRPS25 (mitochondrial ribosomal protein S25). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in whole brain E14.5 (RPKM 14.0), cortex adult (RPKM 13.4) and 27 other tissues See more
    Orthologs
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    Genomic context

    See Mrps25 in Genome Data Viewer
    Location:
    6 D1; 6 41.03 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (92146493..92161004, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (92169512..92184023, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene FYVE, RhoGEF and PH domain containing 5 Neighboring gene STARR-positive B cell enhancer ABC_E539 Neighboring gene nuclear receptor subfamily 2, group C, member 2 Neighboring gene predicted gene, 46967 Neighboring gene rabenosyn, RAB effector Neighboring gene STARR-seq mESC enhancer starr_16664 Neighboring gene thyrotropin releasing hormone

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    small ribosomal subunit protein mS25
    Names
    28S ribosomal protein S25, mitochondrial
    MRP-S25
    S25mt
    NP_079854.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025578.4NP_079854.2  small ribosomal subunit protein mS25

      See identical proteins and their annotated locations for NP_079854.2

      Status: VALIDATED

      Source sequence(s)
      AC164642
      Consensus CDS
      CCDS20373.1
      UniProtKB/Swiss-Prot
      Q9CYY8, Q9D125
      UniProtKB/TrEMBL
      Q6KAU3
      Related
      ENSMUSP00000114402.2, ENSMUST00000140438.2
      Conserved Domains (1) summary
      smart00916
      Location:43107
      L51_S25_CI-B8; Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      92146493..92161004 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)