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    Lgals7 lectin, galactose binding, soluble 7 [ Mus musculus (house mouse) ]

    Gene ID: 16858, updated on 3-Dec-2024

    Summary

    Official Symbol
    Lgals7provided by MGI
    Official Full Name
    lectin, galactose binding, soluble 7provided by MGI
    Primary source
    MGI:MGI:1316742
    See related
    Ensembl:ENSMUSG00000053522 AllianceGenome:MGI:1316742
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Pig1; Galectin-7
    Summary
    Predicted to enable carbohydrate binding activity. Predicted to be involved in apoptotic process. Is active in cornified envelope. Is expressed in maxillary process and upper jaw. Orthologous to human LGALS7 (galectin 7) and LGALS7B (galectin 7B). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in stomach adult (RPKM 383.9), lung adult (RPKM 28.9) and 1 other tissue See more
    Orthologs
    NEW
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    Genomic context

    See Lgals7 in Genome Data Viewer
    Location:
    7 B1; 7 16.94 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (28563258..28565711)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (28863796..28866285)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_18440 Neighboring gene enoyl coenzyme A hydratase 1, peroxisomal Neighboring gene lectin, galactose binding, soluble 4 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:29650992-29651179 Neighboring gene predicted gene 10648 Neighboring gene calpain 12 Neighboring gene predicted gene 44700

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Gene trapped (1) 
    • Targeted (3)  1 citation

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC151215, MGC151217

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables carbohydrate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cornified envelope IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001403038.1NP_001389967.1  galectin-7

      Status: VALIDATED

      Source sequence(s)
      AC171210
      UniProtKB/TrEMBL
      D3Z141, Q9CRB1, Q9D7K4
      Related
      ENSMUSP00000123110.3, ENSMUST00000138272.9
    2. NM_008496.5NP_032522.2  galectin-7

      See identical proteins and their annotated locations for NP_032522.2

      Status: VALIDATED

      Source sequence(s)
      AC171210
      Consensus CDS
      CCDS21060.1
      UniProtKB/TrEMBL
      D3Z141, Q9CRB1, Q9D7K4
      Related
      ENSMUSP00000080179.5, ENSMUST00000081457.5
      Conserved Domains (1) summary
      pfam00337
      Location:5133
      Gal-bind_lectin; Galactoside-binding lectin

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      28563258..28565711
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)