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    Zcchc24 zinc finger, CCHC domain containing 24 [ Mus musculus (house mouse) ]

    Gene ID: 71918, updated on 24-Dec-2024

    Summary

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    Official Symbol
    Zcchc24provided by MGI
    Official Full Name
    zinc finger, CCHC domain containing 24provided by MGI
    Primary source
    MGI:MGI:1919168
    See related
    Ensembl:ENSMUSG00000055538 AllianceGenome:MGI:1919168
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2310047A01Rik
    Summary
    Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to act upstream of or within regulation of gliogenesis. Orthologous to human ZCCHC24 (zinc finger CCHC-type containing 24). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in subcutaneous fat pad adult (RPKM 45.1), mammary gland adult (RPKM 33.6) and 27 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Zcchc24 in Genome Data Viewer
    Location:
    14 A3; 14 15.06 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (25712068..25769496, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (25711644..25769072, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700054O19 gene Neighboring gene peptidylprolyl isomerase F, opposite strand Neighboring gene peptidylprolyl isomerase F (cyclophilin F) Neighboring gene STARR-seq mESC enhancer starr_36222 Neighboring gene STARR-positive B cell enhancer mm9_chr14:26567064-26567365 Neighboring gene STARR-seq mESC enhancer starr_36224 Neighboring gene STARR-seq mESC enhancer starr_36226 Neighboring gene STARR-seq mESC enhancer starr_36227 Neighboring gene annexin A11 Neighboring gene placenta specific 9 Neighboring gene predicted gene, 57811

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Sox9 and NFIA coordinate a transcriptional regulatory cascade during the initiation of gliogenesis. Kang P, et al. Neuron, 2012 Apr 12. PMID 22500632, Free PMC Article
    2. Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Bedogni F, et al. Front Mol Neurosci, 2021. PMID 34321999, Free PMC Article
    3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of gliogenesis ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger CCHC domain-containing protein 24

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001101433.2 → NP_001094903.1  zinc finger CCHC domain-containing protein 24

      See identical proteins and their annotated locations for NP_001094903.1

      Status: VALIDATED

      Source sequence(s)
      AC154759, AC164303
      Consensus CDS
      CCDS49419.1
      UniProtKB/Swiss-Prot
      B2RVL6
      Related
      ENSMUSP00000068677.7, ENSMUST00000069180.8
      Conserved Domains (2) summary
      COG5222
      Location:58 → 157
      COG5222; Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only]
      pfam17180
      Location:164 → 230
      zf-3CxxC_2; Zinc-binding domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      25712068..25769496 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B2RVL6.1 GenPept UniProtKB/Swiss-Prot:B2RVL6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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