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    2810408A11Rik RIKEN cDNA 2810408A11 gene [ Mus musculus (house mouse) ]

    Gene ID: 70419, updated on 9-Dec-2024

    Summary

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    Official Symbol
    2810408A11Rikprovided by MGI
    Official Full Name
    RIKEN cDNA 2810408A11 geneprovided by MGI
    Primary source
    MGI:MGI:1917669
    See related
    Ensembl:ENSMUSG00000018570 AllianceGenome:MGI:1917669
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700019L01Rik; 4930470J18Rik
    Summary
    Predicted to enable protein phosphatase inhibitor activity. Predicted to be involved in intracellular signal transduction. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in testis adult (RPKM 34.3), CNS E11.5 (RPKM 3.3) and 4 other tissues See more
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    Genomic context

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    See 2810408A11Rik in Genome Data Viewer
    Location:
    11 B3; 11 42.92 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (69788178..69791867, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (69897352..69901039, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_29868 Neighboring gene potassium channel tetramerisation domain containing 11 Neighboring gene microRNA 6924 Neighboring gene ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:69708255-69708446 Neighboring gene STARR-positive B cell enhancer ABC_E7007 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:69715057-69715244 Neighboring gene neuralized E3 ubiquitin protein ligase 4 Neighboring gene STARR-positive B cell enhancer ABC_E5243 Neighboring gene G protein pathway suppressor 2 Neighboring gene eukaryotic translation initiation factor 5A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
    2. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein phosphatase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    protein phosphatase inhibitor 2-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001316696.2 → NP_001303625.1  protein phosphatase inhibitor 2-like isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL596185
      Consensus CDS
      CCDS83828.1
      UniProtKB/TrEMBL
      B1AR42, Q9CZ35
      Related
      ENSMUSP00000018714.7, ENSMUST00000018714.13
      Conserved Domains (1) summary
      pfam04979
      Location:153 → 258
      IPP-2; Protein phosphatase inhibitor 2 (IPP-2)

    2. NM_001316697.2 → NP_001303626.1  protein phosphatase inhibitor 2-like isoform 3

      Status: VALIDATED

      Source sequence(s)
      AL596185
      Consensus CDS
      CCDS83827.1
      UniProtKB/TrEMBL
      B1AR39, Q9CZ35
      Related
      ENSMUSP00000098529.3, ENSMUST00000100969.9
      Conserved Domains (1) summary
      pfam04979
      Location:153 → 253
      IPP-2; Protein phosphatase inhibitor 2 (IPP-2)

    3. NM_001316698.2 → NP_001303627.1  protein phosphatase inhibitor 2-like isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL596185
      UniProtKB/TrEMBL
      Q3TAR5
      Conserved Domains (1) summary
      pfam04979
      Location:31 → 136
      IPP-2; Protein phosphatase inhibitor 2 (IPP-2)

    4. NM_001363161.1 → NP_001350090.1  protein phosphatase inhibitor 2-like isoform 5

      Status: VALIDATED

      Source sequence(s)
      AK013042, AL596185
      UniProtKB/TrEMBL
      Q9CZ35
      Related
      ENSMUST00000137122.8
      Conserved Domains (1) summary
      pfam04979
      Location:153 → 268
      IPP-2; Protein phosphatase inhibitor 2 (IPP-2)

    5. NM_001382460.1 → NP_001369389.1  protein phosphatase inhibitor 2-like isoform 6

      Status: VALIDATED

      Source sequence(s)
      AL596185
      UniProtKB/TrEMBL
      A0JLP5
      Conserved Domains (1) summary
      pfam04979
      Location:31 → 146
      IPP-2; Protein phosphatase inhibitor 2 (IPP-2)

    6. NM_001382461.1 → NP_001369390.1  protein phosphatase inhibitor 2-like isoform 7

      Status: VALIDATED

      Source sequence(s)
      AL596185
      UniProtKB/TrEMBL
      B1AR44
      Conserved Domains (1) summary
      pfam04979
      Location:153 → 268
      IPP-2; Protein phosphatase inhibitor 2 (IPP-2)

    7. NM_001382462.1 → NP_001369391.1  protein phosphatase inhibitor 2-like isoform 8

      Status: VALIDATED

      Source sequence(s)
      AL596185
      UniProtKB/TrEMBL
      Q9CZ35
      Conserved Domains (1) summary
      pfam04979
      Location:153 → 268
      IPP-2; Protein phosphatase inhibitor 2 (IPP-2)

    8. NM_001382463.1 → NP_001369392.1  protein phosphatase inhibitor 2-like isoform 9

      Status: VALIDATED

      Source sequence(s)
      AL596185
      UniProtKB/TrEMBL
      Q05BD3
      Conserved Domains (1) summary
      pfam04979
      Location:153 → 289
      IPP-2; Protein phosphatase inhibitor 2 (IPP-2)

    9. NM_027419.4 → NP_081695.2  protein phosphatase inhibitor 2-like isoform 1

      See identical proteins and their annotated locations for NP_081695.2

      Status: VALIDATED

      Source sequence(s)
      AL596185
      Consensus CDS
      CCDS24920.1
      UniProtKB/TrEMBL
      Q6NSU2, Q9CZ35
      Related
      ENSMUSP00000099640.4, ENSMUST00000102580.10
      Conserved Domains (1) summary
      pfam04979
      Location:153 → 258
      IPP-2; Protein phosphatase inhibitor 2 (IPP-2)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      69788178..69791867 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036156980.1 → XP_036012873.1  protein phosphatase inhibitor 2-like isoform X2

      Conserved Domains (1) summary
      pfam04979
      Location:153 → 289
      IPP-2; Protein phosphatase inhibitor 2 (IPP-2)

    2. XM_036156981.1 → XP_036012874.1  protein phosphatase inhibitor 2-like isoform X3

      UniProtKB/TrEMBL
      A0JLP5
      Conserved Domains (1) summary
      pfam04979
      Location:31 → 146
      IPP-2; Protein phosphatase inhibitor 2 (IPP-2)

    3. XM_011249246.4 → XP_011247548.1  protein phosphatase inhibitor 2-like isoform X1

      See identical proteins and their annotated locations for XP_011247548.1

      UniProtKB/TrEMBL
      B1AR44
      Conserved Domains (1) summary
      pfam04979
      Location:153 → 268
      IPP-2; Protein phosphatase inhibitor 2 (IPP-2)

    RNA

    1. XR_004937023.1 RNA Sequence

    2. XR_004937022.1 RNA Sequence

    3. XR_004937021.1 RNA Sequence

    4. XR_003949504.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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