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    RRN9 Rrn9p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855312, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RRN9
    Official Full Name
    Rrn9p
    Primary source
    SGD:S000004883
    Locus tag
    YMR270C
    See related
    AllianceGenome:SGD:S000004883; FungiDB:YMR270C; VEuPathDB:YMR270C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables RNA polymerase I general transcription initiation factor activity and TBP-class protein binding activity. Involved in nucleolar large rRNA transcription by RNA polymerase I. Located in nucleolus. Part of RNA polymerase I upstream activating factor complex. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See RRN9 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (805326..806423, complement)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene U6 snRNP complex subunit PRP24 Neighboring gene Tma23p Neighboring gene orotate phosphoribosyltransferase URA10 Neighboring gene tRNA-Gln

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The composition of the RNA polymerase I transcription machinery switches from initiation to elongation mode. Bier M, et al. FEBS Lett, 2004 Apr 23. PMID 15094040
    2. RNA polymerase switch in transcription of yeast rDNA: role of transcription factor UAF (upstream activation factor) in silencing rDNA transcription by RNA polymerase II. Vu L, et al. Proc Natl Acad Sci U S A, 1999 Apr 13. PMID 10200272, Free PMC Article
    3. Multiprotein transcription factor UAF interacts with the upstream element of the yeast RNA polymerase I promoter and forms a stable preinitiation complex. Keys DA, et al. Genes Dev, 1996 Apr 1. PMID 8846924
    4. Histones H3 and H4 are components of upstream activation factor required for the high-level transcription of yeast rDNA by RNA polymerase I. Keener J, et al. Proc Natl Acad Sci U S A, 1997 Dec 9. PMID 9391047, Free PMC Article
    5. Interaction of TATA-binding protein with upstream activation factor is required for activated transcription of ribosomal DNA by RNA polymerase I in Saccharomyces cerevisiae in vivo. Steffan JS, et al. Mol Cell Biol, 1998 Jul. PMID 9632758, Free PMC Article

    See all (39) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables RNA polymerase I general transcription initiation factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables TBP-class protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables TBP-class protein binding IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables TBP-class protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in nucleolar large rRNA transcription by RNA polymerase I IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in nucleolar large rRNA transcription by RNA polymerase I IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of RNA polymerase I upstream activating factor complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Rrn9p
    NP_013997.1
    • Protein involved in promoting high level transcription of rDNA; subunit of UAF (upstream activation factor) for RNA polymerase I

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      805326..806423 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182777.1 → NP_013997.1  TPA: Rrn9p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013997.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W096, E9P918, P53437
      UniProtKB/TrEMBL
      A6ZMY5, B3LMF7, B5VQ34, C7GR84, N1NZ51
      Conserved Domains (1) summary
      pfam10680
      Location:47 → 103
      RRN9; RNA polymerase I specific transcription initiation factor
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53437.1

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