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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_029507.2 RefSeqGene
- Range
-
5002..35223
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001301022.2 → NP_001287951.1 diphosphoinositol polyphosphate phosphohydrolase 2 isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) contains an alternate 5' terminal exon, resulting in the use of a downstream start codon compared to variant 2. The encoded isoform (3) has a shorter N-terminus compared to isoform beta.
- Source sequence(s)
-
AC025260, AK304296
- Consensus CDS
-
CCDS73504.1
- UniProtKB/TrEMBL
-
F8VRR0
- Related
- ENSP00000448032.1, ENST00000547014.5
- Conserved Domains (1) summary
-
- cl00447
Location:1 → 86
- Nudix_Hydrolase; Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ ...
-
NM_001301023.2 → NP_001287952.1 diphosphoinositol polyphosphate phosphohydrolase 2 isoform 4
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) contains an alternate 5' terminal exon, and uses an alternate splice site in the 5' coding region, resulting in the use of a downstream start codon compared to variant 2. The encoded isoform (4) has a shorter N-terminus compared to isoform beta. Variants 4 and 5 encode the same isoform.
- Source sequence(s)
-
AC025260, CR749445
- Consensus CDS
-
CCDS76584.1
- UniProtKB/TrEMBL
- A0A0C4DGJ4, F8VRR0
- Related
- ENSP00000449552.1, ENST00000549992.5
- Conserved Domains (1) summary
-
- cl00447
Location:1 → 85
- Nudix_Hydrolase; Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ ...
-
NM_001301024.2 → NP_001287953.1 diphosphoinositol polyphosphate phosphohydrolase 2 isoform 4
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) contains an alternate 5' terminal exon, and uses an alternate splice site in the 5' coding region, resulting in the use of a downstream start codon compared to variant 2. The encoded isoform (4) has a shorter N-terminus compared to isoform beta. Variants 4 and 5 encode the same isoform.
- Source sequence(s)
-
AC025260, BP315657, CN335956
- Consensus CDS
-
CCDS76584.1
- UniProtKB/TrEMBL
- A0A0C4DGJ4, F8VRR0
- Related
- ENSP00000449724.1, ENST00000548662.5
- Conserved Domains (1) summary
-
- cl00447
Location:1 → 85
- Nudix_Hydrolase; Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ ...
-
NM_019094.6 → NP_061967.3 diphosphoinositol polyphosphate phosphohydrolase 2 isoform alpha
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) uses an alternate in-frame splice site in the 5' coding region, compared to variant 2. The encoded protein is the predominant isoform (alpha), and is shorter than isoform beta.
- Source sequence(s)
-
AC025260, AC124947, AF191649
- Consensus CDS
-
CCDS44952.1
- UniProtKB/Swiss-Prot
- B7Z916, Q4AEJ6, Q53EZ2, Q68DD7, Q9NPC5, Q9NS30, Q9NZJ9, Q9NZK0, Q9NZK1
- UniProtKB/TrEMBL
-
B2RE29
- Related
- ENSP00000406612.2, ENST00000415493.7
- Conserved Domains (1) summary
-
- cd04666
Location:19 → 137
- Nudix_Hydrolase_9; Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly ...
-
NM_199040.4 → NP_950241.1 diphosphoinositol polyphosphate phosphohydrolase 2 isoform beta
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) represents the longest transcript and encodes the longest isoform (beta).
- Source sequence(s)
-
AC025260, AC090050, AC124947, AK223497
- Consensus CDS
-
CCDS9044.1
- UniProtKB/Swiss-Prot
-
A0A024RBG1
- UniProtKB/TrEMBL
-
B2RE29
- Related
- ENSP00000338352.5, ENST00000337179.9
- Conserved Domains (1) summary
-
- cd04666
Location:19 → 138
- Nudix_Hydrolase_9; Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly ...