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    LINC02914 long intergenic non-protein coding RNA 2914 [ Homo sapiens (human) ]

    Gene ID: 283598, updated on 10-Dec-2024

    Summary

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    Official Symbol
    LINC02914provided by HGNC
    Official Full Name
    long intergenic non-protein coding RNA 2914provided by HGNC
    Primary source
    HGNC:HGNC:26375
    See related
    Ensembl:ENSG00000176605 AllianceGenome:HGNC:26375
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    C14orf177
    Summary
    Predicted to be located in cytoplasm; motile cilium; and nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    all
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    Genomic context

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    See LINC02914 in Genome Data Viewer
    Location:
    14q32.2
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 14 NC_000014.9 (98711613..98717766)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 14 NC_060938.1 (92943252..92949407)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (99177950..99184103)

    Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene RNA, 7SL, cytoplasmic 714, pseudogene Neighboring gene NANOG hESC enhancer GRCh37_chr14:98912000-98912501 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr14:98960824-98962023 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr14:98967301-98968500 Neighboring gene uncharacterized LOC105370657 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr14:99117229-99117849 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:99203505-99204004 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:99206799-99207299 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_39017 Neighboring gene uncharacterized LOC124903403 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:99285865-99286462 Neighboring gene uncharacterized LOC105370658

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. Genome-wide linkage analyses of non-Hispanic white families identify novel loci for familial late-onset Alzheimer's disease. Kunkle BW, et al. Alzheimers Dement, 2016 Jan. PMID 26365416, Free PMC Article
    2. Validating Missing Proteins in Human Sperm Cells by Targeted Mass-Spectrometry- and Antibody-based Methods. Carapito C, et al. J Proteome Res, 2017 Dec 1. PMID 28891297
    3. Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy. Chu AY, et al. Circ Cardiovasc Genet, 2012 Dec. PMID 23118302
    4. Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. Yang Q, et al. BMC Med Genet, 2007 Sep 19. PMID 17903294, Free PMC Article
    5. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. Comuzzie AG, et al. PLoS One, 2012. PMID 23251661, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.
    EBI GWAS Catalog
    Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Markers

    Homology

    Clone Names

    • FLJ25773

    Gene Ontology Provided by GOA

    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in motile cilium IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_161367.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL096821

    2. NR_161368.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL096821
      Related
      ENST00000650364.1

    3. NR_161369.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL096821

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000014.9 Reference GRCh38.p14 Primary Assembly

      Range
      98711613..98717766
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060938.1 Alternate T2T-CHM13v2.0

      Range
      92943252..92949407
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001346978.1: Suppressed sequence

      Description
      NM_001346978.1: This RefSeq was removed because it is now thought that this gene does not encode a protein.

    2. NM_001346979.1: Suppressed sequence

      Description
      NM_001346979.1: This RefSeq was removed because it is now thought that this gene does not encode a protein.

    3. NM_182560.2: Suppressed sequence

      Description
      NM_182560.2: This RefSeq was removed because it is now thought that this gene does not encode a protein.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q52M58.1 GenPept UniProtKB/Swiss-Prot:Q52M58

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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