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    MAL13 transcription factor MAL13 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853205, updated on 9-Dec-2024

    Summary

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    Official Symbol
    MAL13
    Official Full Name
    transcription factor MAL13
    Primary source
    SGD:S000003520
    Locus tag
    YGR288W
    See related
    AllianceGenome:SGD:S000003520; FungiDB:YGR288W; VEuPathDB:YGR288W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable DNA-binding transcription factor activity. Involved in carbohydrate metabolic process. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See MAL13 in Genome Data Viewer
    Location:
    chromosome: VII
    Exon count:
    1
    Sequence:
    Chromosome: VII; NC_001139.9 (1070293..1071714)

    Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene biotin synthase Neighboring gene oligo-1,6-glucosidase IMA1 Neighboring gene alpha-glucoside permease Neighboring gene alpha-glucosidase MAL12

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001139.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic mapping and biochemical analysis of mutants in the maltose regulatory gene of the MAL1 locus of Saccharomyces cerevisiae. Goldenthal MJ, et al. Arch Microbiol, 1990. PMID 2278509
    2. Insertion of non-homologous DNA sequences into a regulatory gene cause a constitutive maltase synthesis in yeast. Rodicio R. Curr Genet, 1986. PMID 2834092
    3. Functional domain analysis of the Saccharomyces MAL-activator. Hu Z, et al. Curr Genet, 1999 Aug. PMID 10447589
    4. Duplication of a promiscuous transcription factor drives the emergence of a new regulatory network. Pougach K, et al. Nat Commun, 2014 Sep 10. PMID 25204769, Free PMC Article
    5. Identification of regulatory elements in the AGT1 promoter of ale and lager strains of brewer's yeast. Vidgren V, et al. Yeast, 2011 Aug. PMID 21755532

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in carbohydrate metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in maltose metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transcription factor MAL13
    NP_011804.1
    • MAL-activator protein; part of complex locus MAL1; nonfunctional in genomic reference strain S288C

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001139.9 Reference assembly

      Range
      1070293..1071714
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181417.1 → NP_011804.1  TPA: transcription factor MAL13 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011804.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VV65, P53338
      UniProtKB/TrEMBL
      B0M8X6, E9P8F8, I7LE96, N1P2Z0
      Conserved Domains (2) summary
      cd12148
      Location:84 → 351
      fungal_TF_MHR; fungal transcription factor regulatory middle homology region
      pfam00172
      Location:11 → 48
      Zn_clus; Fungal Zn(2)-Cys(6) binuclear cluster domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53338.1

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