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    Rprm reprimo, TP53 dependent G2 arrest mediator homolog [ Rattus norvegicus (Norway rat) ]

    Gene ID: 680110, updated on 27-Nov-2024

    Summary

    Official Symbol
    Rprmprovided by RGD
    Official Full Name
    reprimo, TP53 dependent G2 arrest mediator homologprovided by RGD
    Primary source
    RGD:1595512
    See related
    EnsemblRapid:ENSRNOG00000005109 AllianceGenome:RGD:1595512
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in regulation of mitotic cell cycle. Predicted to act upstream of or within regulation of cell cycle. Predicted to be located in membrane. Predicted to be active in cytoplasm. Orthologous to human RPRM (reprimo, TP53 dependent G2 arrest mediator homolog). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Uterus (RPKM 76.2), Brain (RPKM 26.1) and 4 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Rprm in Genome Data Viewer
    Location:
    3q12
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (58948618..58950035, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (38539581..38540998, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (39595301..39596718, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA40 Neighboring gene uncharacterized LOC108350373 Neighboring gene U6 spliceosomal RNA Neighboring gene dyskerin pseudouridine synthase 1, pseudogene 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Markers

    Clone Names

    • MGC109515

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within regulation of mitotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein reprimo
    Names
    candidate mediator of the p53-dependent G2 arrest
    reprimo, TP53 dependent G2 arrest mediator candidate

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001044276.1NP_001037741.1  protein reprimo

      See identical proteins and their annotated locations for NP_001037741.1

      Status: PROVISIONAL

      Source sequence(s)
      BC091400
      UniProtKB/Swiss-Prot
      Q5BJN9
      UniProtKB/TrEMBL
      A6JF35
      Related
      ENSRNOP00000006784.1, ENSRNOT00000006784.5

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      58948618..58950035 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)