narG nitrate reductase A subunit alpha [Escherichia coli str. K-12 substr. MG1655] - Gene

Summary

Official Symbol: narG
Official Full Name: nitrate reductase A subunit alpha
Primary source: ECOCYC:EG10638
Locus tag: b1224
See related: ASAP:ABE-0004119
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage: Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as: chlC; ECK1218; narC
Summary: Induced by anaerobiosis plus nitrate. [More information is available at EcoGene: EG10638]. The subunit of nitrate reductase A is the actual site of nitrate reduction and also contains the molybdenum cofactor . [More information is available at EcoCyc: EG10638].
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NC_000913.3 Genomic Context describing neighboring genes

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analysis of the role of the FS0 cluster of Escherichia coli nitrate reductase A (NarGHI) in enzyme maturation
Title: Protein crystallography reveals a role for the FS0 cluster of Escherichia coli nitrate reductase A (NarGHI) in enzyme maturation.
Conversion of tryptophan and sodium nitrate into 3-nitrosoindole derivatives requires functional genes for trytophanase (tnaA), a tryptophan permease (tnaB), and a nitrate reductase (narG).
Title: Production of 3-nitrosoindole derivatives by Escherichia coli during anaerobic growth.
NarJ associated with a peptide of the first 50 residues of nitrate reductase catalytic subunit NarG.
Title: In vivo associations of Escherichia coli NarJ with a peptide of the first 50 residues of nitrate reductase catalytic subunit NarG.
N-terminus verified by Edman degradation on mature peptide
Title: Roles of the narJ and narI gene products in the expression of nitrate reductase in Escherichia coli.
molecular characterization of a quinol binding and oxidation site (Q-site) in NarGHI
Title: Structural and biochemical characterization of a quinol binding site of Escherichia coli nitrate reductase A.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables 4 iron, 4 sulfur cluster binding	IDA Inferred from Direct Assay more info	PubMed
enables 4 iron, 4 sulfur cluster binding	IEA Inferred from Electronic Annotation more info
enables electron transfer activity	IDA Inferred from Direct Assay more info	PubMed
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables molybdopterin cofactor binding	IDA Inferred from Direct Assay more info	PubMed
enables molybdopterin cofactor binding	IEA Inferred from Electronic Annotation more info
enables nitrate reductase (quinone) activity	IEA Inferred from Electronic Annotation more info
enables nitrate reductase activity	EXP Inferred from Experiment more info	PubMed
enables nitrate reductase activity	IDA Inferred from Direct Assay more info	PubMed
enables nitrate reductase activity	IEA Inferred from Electronic Annotation more info
enables nitrate reductase activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in anaerobic electron transport chain	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within anaerobic respiration	IEP Inferred from Expression Pattern more info	PubMed
involved_in cellular respiration	IEA Inferred from Electronic Annotation more info
involved_in nitrate assimilation	IEA Inferred from Electronic Annotation more info
involved_in nitrate metabolic process	IDA Inferred from Direct Assay more info	PubMed
involved_in nitrate metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within nitrate metabolic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of NarGHI complex	IDA Inferred from Direct Assay more info	PubMed
part_of NarGHI complex	IPI Inferred from Physical Interaction more info	PubMed
located_in membrane	HDA more info	PubMed
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IDA Inferred from Direct Assay more info	PubMed
part_of nitrate reductase complex	IEA Inferred from Electronic Annotation more info
part_of oxidoreductase complex	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

NP_415742.1

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The following sections contain reference sequences that belong to a specific genome build. Explain