Pla2g6 phospholipase A2, group VI [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Pla2g6provided by MGI
Official Full Name: phospholipase A2, group VIprovided by MGI
Primary source: MGI:MGI:1859152
See related: Ensembl:ENSMUSG00000042632 AllianceGenome:MGI:1859152
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: iPLA2; PNPLA9; iPLA2beta; iPLA(2)beta
Summary: Enables calcium-independent phospholipase A2 activity; long-chain fatty acyl-CoA hydrolase activity; and serine hydrolase activity. Involved in positive regulation of insulin secretion involved in cellular response to glucose stimulus. Predicted to be located in several cellular components, including extracellular space; microtubule cytoskeleton; and nuclear speck. Predicted to be active in mitochondrion. Is expressed in 1st branchial arch maxillary component; olfactory placode; otic pit; and trunk somite. Used to study Parkinson's disease 14 and neurodegeneration with brain iron accumulation 2a. Human ortholog(s) of this gene implicated in dystonia 12; neuroaxonal dystrophy; and neurodegenerative disease (multiple). Orthologous to human PLA2G6 (phospholipase A2 group VI). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Broad expression in testis adult (RPKM 76.7), adrenal adult (RPKM 14.0) and 23 other tissues See more
Orthologs: human all
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Genomic context

Location:: 15 E1; 15 37.7 cM

Exon count:: 23

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	15	NC_000081.7 (79170428..79212915, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	15	NC_000081.6 (79286228..79328385, complement)

Chromosome 15 - NC_000081.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

iPLA2beta loss leads to age-related cognitive decline and neuroinflammation by disrupting neuronal mitophagy.
Title: iPLA2β loss leads to age-related cognitive decline and neuroinflammation by disrupting neuronal mitophagy.
Myeloid-specific deletion of group VIA calcium-independent phospholipase A2 induces pro-inflammatory LPS response predominantly in male mice via MIP-1alpha activation.
Title: Myeloid-specific deletion of group VIA calcium-independent phospholipase A2 induces pro-inflammatory LPS response predominantly in male mice via MIP-1α activation.
PLA2G6 mutations cause motor dysfunction phenotypes of young-onset dystonia-parkinsonism type 14 and can be relieved by DHA treatment in animal models.
Title: PLA2G6 mutations cause motor dysfunction phenotypes of young-onset dystonia-parkinsonism type 14 and can be relieved by DHA treatment in animal models.
iPLA2beta Contributes to ER Stress-Induced Apoptosis during Myocardial Ischemia/Reperfusion Injury.
Title: iPLA(2)β Contributes to ER Stress-Induced Apoptosis during Myocardial Ischemia/Reperfusion Injury.
Rescue of Hepatic Phospholipid Remodeling Defectin iPLA2beta-Null Mice Attenuates Obese but Not Non-Obese Fatty Liver.
Title: Rescue of Hepatic Phospholipid Remodeling Defectin iPLA2β-Null Mice Attenuates Obese but Not Non-Obese Fatty Liver.
Acidic Calcium-Independent Phospholipase A2 Regulates Eosinophil-Mediated Pathology during Filarial Manifestation of Tropical Pulmonary Eosinophilia.
Title: Acidic Calcium-Independent Phospholipase A2 Regulates Eosinophil-Mediated Pathology during Filarial Manifestation of Tropical Pulmonary Eosinophilia.
iPLA2beta-mediated lipid detoxification controls p53-driven ferroptosis independent of GPX4.
Title: iPLA2β-mediated lipid detoxification controls p53-driven ferroptosis independent of GPX4.
Metabolic Effects of Selective Deletion of Group VIA Phospholipase A2 from Macrophages or Pancreatic Islet Beta-Cells.
Title: Metabolic Effects of Selective Deletion of Group VIA Phospholipase A(2) from Macrophages or Pancreatic Islet Beta-Cells.
Type 1 interferon-dependent repression of NLRC4 and iPLA2 licenses down-regulation of Salmonella flagellin inside macrophages.
Title: Type 1 interferon-dependent repression of NLRC4 and iPLA2 licenses down-regulation of Salmonella flagellin inside macrophages.
This study provides insights into iPla2b (PLA2G6) inactivation for injury susceptibility under normal conditions and liver fibrosis and cholangiopathies during methionine-choline-deficient diet feeding.
Title: iPla2β Deficiency Suppresses Hepatic ER UPR, Fxr, and Phospholipids in Mice Fed with MCD Diet, Resulting in Exacerbated Hepatic Bile Acids and Biliary Cell Proliferation.

Submit: New GeneRIF Correction See all GeneRIFs (74)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Chemically induced (ENU) (1)
Endonuclease-mediated (4)
Spontaneous (1) 1 citation
Targeted (8) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Pla2g6 (e-PCR), detects polymorphism
- UniSTS:507148

NoName (e-PCR)
- UniSTS:237347

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables 1-alkyl-2-acetylglycerophosphocholine esterase activity	ISS Inferred from Sequence or Structural Similarity more info
enables ATP-dependent protein binding	ISO Inferred from Sequence Orthology more info
enables calcium-dependent phospholipase A2 activity	IEA Inferred from Electronic Annotation more info
enables calcium-independent phospholipase A2 activity	IBA Inferred from Biological aspect of Ancestor more info
enables calcium-independent phospholipase A2 activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables calcium-independent phospholipase A2 activity	ISO Inferred from Sequence Orthology more info
enables calcium-independent phospholipase A2 activity	ISS Inferred from Sequence or Structural Similarity more info
enables calmodulin binding	IEA Inferred from Electronic Annotation more info
enables identical protein binding	IEA Inferred from Electronic Annotation more info
enables identical protein binding	ISO Inferred from Sequence Orthology more info
enables long-chain fatty acyl-CoA hydrolase activity	IBA Inferred from Biological aspect of Ancestor more info
enables long-chain fatty acyl-CoA hydrolase activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables long-chain fatty acyl-CoA hydrolase activity	ISO Inferred from Sequence Orthology more info
enables long-chain fatty acyl-CoA hydrolase activity	ISS Inferred from Sequence or Structural Similarity more info
enables lysophospholipase activity	ISO Inferred from Sequence Orthology more info
enables lysophospholipase activity	ISS Inferred from Sequence or Structural Similarity more info
enables protein kinase binding	ISO Inferred from Sequence Orthology more info
enables serine hydrolase activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in antibacterial humoral response	IEA Inferred from Electronic Annotation more info
involved_in antibacterial humoral response	ISO Inferred from Sequence Orthology more info
involved_in cardiolipin acyl-chain remodeling	IBA Inferred from Biological aspect of Ancestor more info
involved_in cardiolipin acyl-chain remodeling	ISO Inferred from Sequence Orthology more info
involved_in cardiolipin acyl-chain remodeling	ISS Inferred from Sequence or Structural Similarity more info
involved_in cardiolipin biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in cardiolipin biosynthetic process	ISO Inferred from Sequence Orthology more info
involved_in chemotaxis	IEA Inferred from Electronic Annotation more info
involved_in memory	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of synaptic transmission, glutamatergic	ISO Inferred from Sequence Orthology more info
involved_in phosphatidic acid metabolic process	ISS Inferred from Sequence or Structural Similarity more info
involved_in phosphatidylcholine catabolic process	ISO Inferred from Sequence Orthology more info
involved_in phosphatidylcholine catabolic process	ISS Inferred from Sequence or Structural Similarity more info
involved_in phosphatidylethanolamine catabolic process	ISS Inferred from Sequence or Structural Similarity more info
involved_in platelet activating factor metabolic process	ISS Inferred from Sequence or Structural Similarity more info
involved_in positive regulation of arachidonate secretion	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of ceramide biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of ceramide biosynthetic process	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of cytosolic calcium ion concentration	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of exocytosis	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of insulin secretion involved in cellular response to glucose stimulus	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of insulin secretion involved in cellular response to glucose stimulus	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of protein kinase C signaling	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of protein phosphorylation	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of release of cytochrome c from mitochondria	ISO Inferred from Sequence Orthology more info
involved_in response to endoplasmic reticulum stress	ISO Inferred from Sequence Orthology more info
involved_in urinary bladder smooth muscle contraction	ISO Inferred from Sequence Orthology more info
involved_in vasodilation	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in extracellular space	IEA Inferred from Electronic Annotation more info
located_in extracellular space	ISO Inferred from Sequence Orthology more info
located_in microtubule cytoskeleton	IEA Inferred from Electronic Annotation more info
located_in microtubule cytoskeleton	ISO Inferred from Sequence Orthology more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
located_in nuclear speck	IEA Inferred from Electronic Annotation more info
located_in nuclear speck	ISO Inferred from Sequence Orthology more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info
located_in pseudopodium	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: 85/88 kDa calcium-independent phospholipase A2

Names: 2-lysophosphatidylcholine acylhydrolase; 85 kDa calcium-independent phospholipase A2; GVI PLA2; caI-PLA2; group VI phospholipase A2; iPLA2-beta; intracellular membrane-associated calcium-independent phospholipase A2 beta; palmitoyl-CoA hydrolase; patatin-like phospholipase domain-containing protein 9

NP_001185952.1

EC 3.1.1.4

EC 3.1.1.5

EC 3.1.2.2

NP_001185953.1

EC 3.1.1.4

EC 3.1.1.5

EC 3.1.2.2

NP_001185954.1

EC 3.1.1.4

EC 3.1.1.5

EC 3.1.2.2

NP_001403319.1

EC 3.1.1.4

EC 3.1.1.5

EC 3.1.2.2

NP_001403320.1

EC 3.1.1.4

EC 3.1.1.5

EC 3.1.2.2

NP_001403321.1

EC 3.1.1.4

EC 3.1.1.5

EC 3.1.2.2

NP_001403322.1

EC 3.1.1.4

EC 3.1.1.5

EC 3.1.2.2

NP_001403324.1

EC 3.1.1.4

EC 3.1.1.5

EC 3.1.2.2

NP_001403325.1

EC 3.1.1.4

EC 3.1.1.5

EC 3.1.2.2

NP_001403326.1

EC 3.1.1.4

EC 3.1.1.5

EC 3.1.2.2

NP_001403327.1

EC 3.1.1.4

EC 3.1.1.5

EC 3.1.2.2

NP_001403328.1

EC 3.1.1.4

EC 3.1.1.5

EC 3.1.2.2

NP_001403329.1

EC 3.1.1.4

EC 3.1.1.5

EC 3.1.2.2

NP_001403333.1

EC 3.1.1.4

EC 3.1.1.5

EC 3.1.2.2

NP_058611.1

EC 3.1.1.4

EC 3.1.1.5

EC 3.1.2.2

XP_036015396.1

EC 3.1.1.4

EC 3.1.1.5

EC 3.1.2.2

XP_036015397.1

EC 3.1.1.4

EC 3.1.1.5

EC 3.1.2.2

XP_036015398.1

EC 3.1.1.4

EC 3.1.1.5

EC 3.1.2.2

XP_036015399.1

EC 3.1.1.4

EC 3.1.1.5

EC 3.1.2.2

XP_036015400.1

EC 3.1.1.4

EC 3.1.1.5

EC 3.1.2.2

XP_036015401.1

EC 3.1.1.4

EC 3.1.1.5

EC 3.1.2.2

XP_036015402.1

EC 3.1.1.4

EC 3.1.1.5

EC 3.1.2.2

XP_036015403.1

EC 3.1.1.4

EC 3.1.1.5

EC 3.1.2.2

XP_036015404.1

EC 3.1.1.4

EC 3.1.1.5

EC 3.1.2.2

XP_036015405.1

EC 3.1.1.4

EC 3.1.1.5

EC 3.1.2.2

XP_036015406.1

EC 3.1.1.4

EC 3.1.1.5

EC 3.1.2.2

XP_036015407.1

EC 3.1.1.4

EC 3.1.1.5

EC 3.1.2.2

XP_036015409.1

EC 3.1.1.4

EC 3.1.1.5

EC 3.1.2.2

XP_036015410.1

EC 3.1.1.4

EC 3.1.1.5

EC 3.1.2.2

XP_036015411.1

EC 3.1.1.4

EC 3.1.1.5

EC 3.1.2.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001199023.2 → NP_001185952.1 85/88 kDa calcium-independent phospholipase A2 isoform 2

See identical proteins and their annotated locations for NP_001185952.1

Status: VALIDATED

Description

Transcript Variant: This variant (2) differs in the 5' UTR and has an additional in-frame exon in the coding region, compared to variant 1. It encodes a longer isoform (2) than isoform 1.

Source sequence(s)

AC165278, AL591913

Consensus CDS

CCDS56991.1

UniProtKB/Swiss-Prot

P97819, Q99LA9, Q9JK61

UniProtKB/TrEMBL

Q3U613, Q7TPX2

Related

ENSMUSP00000134672.2, ENSMUST00000174021.8

Conserved Domains (5) summary

cd07212
Location:481 → 794

Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9

PHA02875
Location:220 → 412

PHA02875; ankyrin repeat protein; Provisional

sd00045
Location:286 → 314

ANK; ANK repeat [structural motif]

pfam12796
Location:156 → 248

Ank_2; Ankyrin repeats (3 copies)

cl39094
Location:103 → 183

Ank_2; Ankyrin repeats (3 copies)
NM_001199024.2 → NP_001185953.1 85/88 kDa calcium-independent phospholipase A2 isoform 1

See identical proteins and their annotated locations for NP_001185953.1

Status: VALIDATED

Description

Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1, and encodes isoform (1). Variants 1, 3, and 4 encode the same protein (isoform 1).

Source sequence(s)

AC165278, AL591913

Consensus CDS

CCDS27637.1

UniProtKB/TrEMBL

Q3U613, Q3UN31, Q7TPX2

Related

ENSMUSP00000132071.3, ENSMUST00000166977.9

Conserved Domains (5) summary

cd07212
Location:426 → 739

Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9

PHA02875
Location:220 → 390

PHA02875; ankyrin repeat protein; Provisional

sd00045
Location:286 → 314

ANK; ANK repeat [structural motif]

pfam12796
Location:156 → 248

Ank_2; Ankyrin repeats (3 copies)

cl39094
Location:103 → 183

Ank_2; Ankyrin repeats (3 copies)
NM_001199025.2 → NP_001185954.1 85/88 kDa calcium-independent phospholipase A2 isoform 1

See identical proteins and their annotated locations for NP_001185954.1

Status: VALIDATED

Description

Transcript Variant: This variant (4) differs in the 5' UTR, compared to variant 1, and encodes isoform (1). Variants 1, 3, and 4 encode the same protein (isoform 1).

Source sequence(s)

AC165278, AL591913

Consensus CDS

CCDS27637.1

UniProtKB/TrEMBL

Q3U613, Q3UN31, Q7TPX2

Related

ENSMUSP00000131081.3, ENSMUST00000172403.9

Conserved Domains (5) summary

cd07212
Location:426 → 739

Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9

PHA02875
Location:220 → 390

PHA02875; ankyrin repeat protein; Provisional

sd00045
Location:286 → 314

ANK; ANK repeat [structural motif]

pfam12796
Location:156 → 248

Ank_2; Ankyrin repeats (3 copies)

cl39094
Location:103 → 183

Ank_2; Ankyrin repeats (3 copies)
NM_001416390.1 → NP_001403319.1 85/88 kDa calcium-independent phospholipase A2 isoform 1

Status: VALIDATED

Source sequence(s)

AC165278, AL591913

UniProtKB/TrEMBL

Q3UN31
NM_001416391.1 → NP_001403320.1 85/88 kDa calcium-independent phospholipase A2 isoform 1

Status: VALIDATED

Source sequence(s)

AC165278, AL591913

UniProtKB/TrEMBL

Q3UN31

Related

ENSMUSP00000134456.2, ENSMUST00000173163.8
NM_001416392.1 → NP_001403321.1 85/88 kDa calcium-independent phospholipase A2 isoform 1

Status: VALIDATED

Source sequence(s)

AC165278, AL591913

UniProtKB/TrEMBL

Q3UN31
NM_001416393.1 → NP_001403322.1 85/88 kDa calcium-independent phospholipase A2 isoform 1

Status: VALIDATED

Source sequence(s)

AC165278, AL591913

UniProtKB/TrEMBL

Q3UN31
NM_001416395.1 → NP_001403324.1 85/88 kDa calcium-independent phospholipase A2 isoform 1

Status: VALIDATED

Source sequence(s)

AL591913

UniProtKB/TrEMBL

Q3UN31
NM_001416396.1 → NP_001403325.1 85/88 kDa calcium-independent phospholipase A2 isoform 2

Status: VALIDATED

Source sequence(s)

AC165278, AL591913

UniProtKB/Swiss-Prot

P97819, Q99LA9, Q9JK61
NM_001416397.1 → NP_001403326.1 85/88 kDa calcium-independent phospholipase A2 isoform 2

Status: VALIDATED

Source sequence(s)

AC165278, AL591913

UniProtKB/Swiss-Prot

P97819, Q99LA9, Q9JK61
NM_001416398.1 → NP_001403327.1 85/88 kDa calcium-independent phospholipase A2 isoform 2

Status: VALIDATED

Source sequence(s)

AC165278, AL591913

UniProtKB/Swiss-Prot

P97819, Q99LA9, Q9JK61
NM_001416399.1 → NP_001403328.1 85/88 kDa calcium-independent phospholipase A2 isoform 2

Status: VALIDATED

Source sequence(s)

AC165278, AL591913

UniProtKB/Swiss-Prot

P97819, Q99LA9, Q9JK61
NM_001416400.1 → NP_001403329.1 85/88 kDa calcium-independent phospholipase A2 isoform 3

Status: VALIDATED

Source sequence(s)

AC165278, AL591913
NM_001416404.1 → NP_001403333.1 85/88 kDa calcium-independent phospholipase A2 isoform 4

Status: VALIDATED

Source sequence(s)

AC165278, AL591913
NM_016915.5 → NP_058611.1 85/88 kDa calcium-independent phospholipase A2 isoform 1

See identical proteins and their annotated locations for NP_058611.1

Status: VALIDATED

Description

Transcript Variant: This variant (1) represents the shortest transcript and encodes the shorter isoform (1). Variants 1, 3, and 4 encode the same protein (isoform 1).

Source sequence(s)

AC165278, AL591913

Consensus CDS

CCDS27637.1

UniProtKB/TrEMBL

Q3U613, Q3UN31, Q7TPX2

Related

ENSMUSP00000044234.9, ENSMUST00000047816.15

Conserved Domains (5) summary

cd07212
Location:426 → 739

Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9

PHA02875
Location:220 → 390

PHA02875; ankyrin repeat protein; Provisional

sd00045
Location:286 → 314

ANK; ANK repeat [structural motif]

pfam12796
Location:156 → 248

Ank_2; Ankyrin repeats (3 copies)

cl39094
Location:103 → 183

Ank_2; Ankyrin repeats (3 copies)

RNA

NR_183841.1 RNA Sequence

Status: VALIDATED

Source sequence(s)

AC165278, AL591913

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000081.7 Reference GRCm39 C57BL/6J

Range

79170428..79212915 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_036159506.1 → XP_036015399.1 85/88 kDa calcium-independent phospholipase A2 isoform X1

Conserved Domains (5) summary

cd07212
Location:481 → 940

Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9

PHA02875
Location:220 → 412

PHA02875; ankyrin repeat protein; Provisional

sd00045
Location:286 → 314

ANK; ANK repeat [structural motif]

pfam12796
Location:156 → 249

Ank_2; Ankyrin repeats (3 copies)

cl39094
Location:103 → 183

Ank_2; Ankyrin repeats (3 copies)
XM_036159511.1 → XP_036015404.1 85/88 kDa calcium-independent phospholipase A2 isoform X1

Conserved Domains (5) summary

cd07212
Location:481 → 940

Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9

PHA02875
Location:220 → 412

PHA02875; ankyrin repeat protein; Provisional

sd00045
Location:286 → 314

ANK; ANK repeat [structural motif]

pfam12796
Location:156 → 249

Ank_2; Ankyrin repeats (3 copies)

cl39094
Location:103 → 183

Ank_2; Ankyrin repeats (3 copies)
XM_036159504.1 → XP_036015397.1 85/88 kDa calcium-independent phospholipase A2 isoform X1

Conserved Domains (5) summary

cd07212
Location:481 → 940

Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9

PHA02875
Location:220 → 412

PHA02875; ankyrin repeat protein; Provisional

sd00045
Location:286 → 314

ANK; ANK repeat [structural motif]

pfam12796
Location:156 → 249

Ank_2; Ankyrin repeats (3 copies)

cl39094
Location:103 → 183

Ank_2; Ankyrin repeats (3 copies)
XM_036159507.1 → XP_036015400.1 85/88 kDa calcium-independent phospholipase A2 isoform X1

Conserved Domains (5) summary

cd07212
Location:481 → 940

Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9

PHA02875
Location:220 → 412

PHA02875; ankyrin repeat protein; Provisional

sd00045
Location:286 → 314

ANK; ANK repeat [structural motif]

pfam12796
Location:156 → 249

Ank_2; Ankyrin repeats (3 copies)

cl39094
Location:103 → 183

Ank_2; Ankyrin repeats (3 copies)
XM_036159514.1 → XP_036015407.1 85/88 kDa calcium-independent phospholipase A2 isoform X2

UniProtKB/TrEMBL

Q3U613, Q7TPX2

Conserved Domains (3) summary

cd07212
Location:426 → 885

Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9

sd00045
Location:286 → 314

ANK; ANK repeat [structural motif]

pfam12796
Location:156 → 249

Ank_2; Ankyrin repeats (3 copies)
XM_036159512.1 → XP_036015405.1 85/88 kDa calcium-independent phospholipase A2 isoform X1

Conserved Domains (5) summary

cd07212
Location:481 → 940

Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9

PHA02875
Location:220 → 412

PHA02875; ankyrin repeat protein; Provisional

sd00045
Location:286 → 314

ANK; ANK repeat [structural motif]

pfam12796
Location:156 → 249

Ank_2; Ankyrin repeats (3 copies)

cl39094
Location:103 → 183

Ank_2; Ankyrin repeats (3 copies)
XM_036159503.1 → XP_036015396.1 85/88 kDa calcium-independent phospholipase A2 isoform X1

Conserved Domains (5) summary

cd07212
Location:481 → 940

Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9

PHA02875
Location:220 → 412

PHA02875; ankyrin repeat protein; Provisional

sd00045
Location:286 → 314

ANK; ANK repeat [structural motif]

pfam12796
Location:156 → 249

Ank_2; Ankyrin repeats (3 copies)

cl39094
Location:103 → 183

Ank_2; Ankyrin repeats (3 copies)
XM_036159505.1 → XP_036015398.1 85/88 kDa calcium-independent phospholipase A2 isoform X1

Conserved Domains (5) summary

cd07212
Location:481 → 940

Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9

PHA02875
Location:220 → 412

PHA02875; ankyrin repeat protein; Provisional

sd00045
Location:286 → 314

ANK; ANK repeat [structural motif]

pfam12796
Location:156 → 249

Ank_2; Ankyrin repeats (3 copies)

cl39094
Location:103 → 183

Ank_2; Ankyrin repeats (3 copies)
XM_036159513.1 → XP_036015406.1 85/88 kDa calcium-independent phospholipase A2 isoform X2

UniProtKB/TrEMBL

Q3U613, Q7TPX2

Conserved Domains (3) summary

cd07212
Location:426 → 885

Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9

sd00045
Location:286 → 314

ANK; ANK repeat [structural motif]

pfam12796
Location:156 → 249

Ank_2; Ankyrin repeats (3 copies)
XM_036159517.1 → XP_036015410.1 85/88 kDa calcium-independent phospholipase A2 isoform X5

Conserved Domains (1) summary

cd07212
Location:26 → 485

Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
XM_036159516.1 → XP_036015409.1 85/88 kDa calcium-independent phospholipase A2 isoform X2

UniProtKB/TrEMBL

Q3U613, Q7TPX2

Conserved Domains (3) summary

cd07212
Location:426 → 885

Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9

sd00045
Location:286 → 314

ANK; ANK repeat [structural motif]

pfam12796
Location:156 → 249

Ank_2; Ankyrin repeats (3 copies)
XM_036159508.1 → XP_036015401.1 85/88 kDa calcium-independent phospholipase A2 isoform X1

Conserved Domains (5) summary

cd07212
Location:481 → 940

Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9

PHA02875
Location:220 → 412

PHA02875; ankyrin repeat protein; Provisional

sd00045
Location:286 → 314

ANK; ANK repeat [structural motif]

pfam12796
Location:156 → 249

Ank_2; Ankyrin repeats (3 copies)

cl39094
Location:103 → 183

Ank_2; Ankyrin repeats (3 copies)
XM_036159509.1 → XP_036015402.1 85/88 kDa calcium-independent phospholipase A2 isoform X1

Conserved Domains (5) summary

cd07212
Location:481 → 940

Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9

PHA02875
Location:220 → 412

PHA02875; ankyrin repeat protein; Provisional

sd00045
Location:286 → 314

ANK; ANK repeat [structural motif]

pfam12796
Location:156 → 249

Ank_2; Ankyrin repeats (3 copies)

cl39094
Location:103 → 183

Ank_2; Ankyrin repeats (3 copies)
XM_036159510.1 → XP_036015403.1 85/88 kDa calcium-independent phospholipase A2 isoform X1

Conserved Domains (5) summary

cd07212
Location:481 → 940

Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9

PHA02875
Location:220 → 412

PHA02875; ankyrin repeat protein; Provisional

sd00045
Location:286 → 314

ANK; ANK repeat [structural motif]

pfam12796
Location:156 → 249

Ank_2; Ankyrin repeats (3 copies)

cl39094
Location:103 → 183

Ank_2; Ankyrin repeats (3 copies)
XM_036159518.1 → XP_036015411.1 85/88 kDa calcium-independent phospholipase A2 isoform X5

Conserved Domains (1) summary

cd07212
Location:26 → 485

Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9