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    Zdhhc19 zinc finger, DHHC domain containing 19 [ Mus musculus (house mouse) ]

    Gene ID: 245308, updated on 27-Nov-2024

    Summary

    Official Symbol
    Zdhhc19provided by MGI
    Official Full Name
    zinc finger, DHHC domain containing 19provided by MGI
    Primary source
    MGI:MGI:2682948
    See related
    Ensembl:ENSMUSG00000052363 AllianceGenome:MGI:2682948
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm616; Gm1744
    Summary
    Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in peptidyl-L-cysteine S-palmitoylation; positive regulation of aggrephagy; and protein targeting to membrane. Predicted to be located in Golgi membrane and perinucleolar compartment. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Orthologous to human ZDHHC19 (zinc finger DHHC-type palmitoyltransferase 19). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward testis adult (RPKM 76.6) See more
    Orthologs
    NEW
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    Genomic context

    See Zdhhc19 in Genome Data Viewer
    Location:
    16 B3; 16 22.76 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (32315059..32326032)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (32496241..32507214)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer mm9_chr16:32430841-32431142 Neighboring gene STARR-positive B cell enhancer ABC_E9428 Neighboring gene phosphate cytidylyltransferase 1, choline, alpha isoform Neighboring gene solute carrier family 51, alpha subunit Neighboring gene STARR-seq mESC enhancer starr_40658 Neighboring gene STARR-seq mESC enhancer starr_40663 Neighboring gene STARR-seq mESC enhancer starr_40664 Neighboring gene STARR-seq mESC enhancer starr_40665 Neighboring gene SET domain containing 6 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E7444 Neighboring gene transferrin receptor

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Clone Names

    • MGC58833

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein-cysteine S-palmitoyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein-cysteine S-palmitoyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein-cysteine S-palmitoyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in peptidyl-L-cysteine S-palmitoylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in peptidyl-L-cysteine S-palmitoylation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of aggrephagy IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of aggrephagy ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein targeting to membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in perinucleolar compartment IEA
    Inferred from Electronic Annotation
    more info
     
    located_in perinucleolar compartment ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    palmitoyltransferase ZDHHC19
    Names
    DHHC-19
    probable palmitoyltransferase ZDHHC19
    zinc finger DHHC domain-containing protein 19
    NP_955013.1
    XP_006522198.1
    XP_011244202.1
    XP_030104974.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199309.2NP_955013.1  palmitoyltransferase ZDHHC19

      See identical proteins and their annotated locations for NP_955013.1

      Status: PROVISIONAL

      Source sequence(s)
      AC140186
      Consensus CDS
      CCDS28122.1
      UniProtKB/Swiss-Prot
      Q810M5
      UniProtKB/TrEMBL
      B9EIU6
      Related
      ENSMUSP00000070727.8, ENSMUST00000064192.8
      Conserved Domains (1) summary
      pfam01529
      Location:109181
      DHHC; DHHC palmitoyltransferase

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      32315059..32326032
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030249114.1XP_030104974.1  palmitoyltransferase ZDHHC19 isoform X2

      Related
      ENSMUSP00000156284.2, ENSMUST00000231510.2
      Conserved Domains (1) summary
      pfam01529
      Location:2682
      DHHC; DHHC palmitoyltransferase
    2. XM_011245900.1XP_011244202.1  palmitoyltransferase ZDHHC19 isoform X1

      UniProtKB/TrEMBL
      B9EIU6
      Conserved Domains (1) summary
      pfam01529
      Location:107179
      DHHC; DHHC palmitoyltransferase
    3. XM_006522135.3XP_006522198.1  palmitoyltransferase ZDHHC19 isoform X2

      Conserved Domains (1) summary
      pfam01529
      Location:2682
      DHHC; DHHC palmitoyltransferase

    RNA

    1. XR_875803.1 RNA Sequence