Glyatl3 glycine-N-acyltransferase-like 3 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Glyatl3provided by MGI
Official Full Name: glycine-N-acyltransferase-like 3provided by MGI
Primary source: MGI:MGI:3647683
See related: Ensembl:ENSMUSG00000091043 AllianceGenome:MGI:3647683
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Gm5683; EG435528
Summary: Enables glycine N-acyltransferase activity. Predicted to be involved in lipid metabolic process. Predicted to be located in mitochondrion. Orthologous to human GLYATL3 (glycine-N-acyltransferase like 3). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Low expression observed in reference dataset See more
Orthologs: human all
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Genomic context

Location:: 17 B2; 17 19.55 cM

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	17	NC_000083.7 (41214599..41229469, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	17	NC_000083.6 (40904727..40923048, complement)

Chromosome 17 - NC_000083.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Knockdown of GLYATL3 in the mouse neuroblastoma cells resulted in a decrease in the levels of the N-acylglycines and the primary fatty acid amides.
Title: Glycine N-acyltransferase-like 3 is responsible for long-chain N-acylglycine formation in N18TG2 cells.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)

General gene information

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Markers

D17Mit272 (e-PCR), detects polymorphism
- UniSTS:128076

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables glycine N-acyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables glycine N-acyltransferase activity	IDA Inferred from Direct Assay more info	PubMed
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in lipid metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: glycine-N-acyltransferase-like protein 3

Names: acyl-CoA:glycine-N-acyltransferase-like protein 3; glycine N-acyltransferase-like protein 3

NP_001138532.1

EC 2.3.1.13

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001145060.2 → NP_001138532.1 glycine-N-acyltransferase-like protein 3

See identical proteins and their annotated locations for NP_001138532.1

Status: VALIDATED

Source sequence(s)

AC121932

Consensus CDS

CCDS50111.1

UniProtKB/Swiss-Prot

E9Q5L8

Related

ENSMUSP00000125916.2, ENSMUST00000166343.3

Conserved Domains (2) summary

pfam06021
Location:10 → 192

Gly_acyl_tr_N; Aralkyl acyl-CoA:amino acid N-acyltransferase

cl17182
Location:193 → 281

NAT_SF; N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate