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    Tpbgl trophoblast glycoprotein-like [ Mus musculus (house mouse) ]

    Gene ID: 100503386, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tpbglprovided by MGI
    Official Full Name
    trophoblast glycoprotein-likeprovided by MGI
    Primary source
    MGI:MGI:3646425
    See related
    Ensembl:ENSMUSG00000096606 AllianceGenome:MGI:3646425
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm4980; EG245190
    Summary
    Predicted to be involved in negative regulation of canonical Wnt signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human TPBGL (trophoblast glycoprotein like). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Tpbgl in Genome Data Viewer
    Location:
    7 E1; 7 54.11 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (99273274..99276310, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (99624067..99627103, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_19659 Neighboring gene predicted gene, 40450 Neighboring gene predicted gene, 34172 Neighboring gene arrestin, beta 1 Neighboring gene microRNA 326 Neighboring gene predicted gene, 53384 Neighboring gene predicted gene, 25409

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Clone Names

    • 6430704N06

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in negative regulation of canonical Wnt signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    trophoblast glycoprotein-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001195529.1NP_001182458.1  trophoblast glycoprotein-like precursor

      See identical proteins and their annotated locations for NP_001182458.1

      Status: VALIDATED

      Source sequence(s)
      AC111086, AK032609
      Consensus CDS
      CCDS57566.1
      UniProtKB/Swiss-Prot
      Q8C013
      Related
      ENSMUSP00000137154.2, ENSMUST00000178124.3
      Conserved Domains (3) summary
      smart00082
      Location:236288
      LRRCT; Leucine rich repeat C-terminal domain
      sd00031
      Location:98121
      LRR_1; leucine-rich repeat [structural motif]
      pfam13855
      Location:96153
      LRR_8; Leucine rich repeat

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      99273274..99276310 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)