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    Sdr42e1 short chain dehydrogenase/reductase family 42E, member 1 [ Mus musculus (house mouse) ]

    Gene ID: 74032, updated on 9-Dec-2024

    Summary

    Official Symbol
    Sdr42e1provided by MGI
    Official Full Name
    short chain dehydrogenase/reductase family 42E, member 1provided by MGI
    Primary source
    MGI:MGI:1921282
    See related
    Ensembl:ENSMUSG00000034308 AllianceGenome:MGI:1921282
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4632417N05Rik
    Summary
    Predicted to enable oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Predicted to be involved in steroid biosynthetic process. Predicted to be located in membrane. Is expressed in several structures, including brain; integumental system; limb; liver; and musculoskeletal system. Orthologous to human SDR42E1 (short chain dehydrogenase/reductase family 42E, member 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in liver adult (RPKM 39.3), bladder adult (RPKM 18.5) and 12 other tissues See more
    Orthologs
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    Genomic context

    See Sdr42e1 in Genome Data Viewer
    Location:
    8 E1; 8 64.69 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (118388138..118400428, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (117661399..117673689, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene c-Maf inducing protein Neighboring gene microRNA 7078 Neighboring gene STARR-positive B cell enhancer ABC_E11399 Neighboring gene phospholipase C, gamma 2 Neighboring gene predicted gene, 31717 Neighboring gene predicted gene, 38416

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    General protein information

    Preferred Names
    short-chain dehydrogenase/reductase family 42E member 1
    NP_001344201.1
    NP_001344202.1
    NP_083001.1
    XP_006531472.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001357272.1NP_001344201.1  short-chain dehydrogenase/reductase family 42E member 1

      Status: VALIDATED

      Source sequence(s)
      AC112964, AK014586, CX243765
      Consensus CDS
      CCDS22701.1
      UniProtKB/Swiss-Prot
      Q8VCV0, Q9D665
      Conserved Domains (1) summary
      cl21454
      Location:10351
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    2. NM_001357273.1NP_001344202.1  short-chain dehydrogenase/reductase family 42E member 1

      Status: VALIDATED

      Source sequence(s)
      AC112964
      Consensus CDS
      CCDS22701.1
      UniProtKB/Swiss-Prot
      Q8VCV0, Q9D665
      Related
      ENSMUSP00000133782.2, ENSMUST00000173522.8
      Conserved Domains (1) summary
      cl21454
      Location:10351
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    3. NM_028725.4NP_083001.1  short-chain dehydrogenase/reductase family 42E member 1

      Status: VALIDATED

      Source sequence(s)
      AC112964
      Consensus CDS
      CCDS22701.1
      UniProtKB/Swiss-Prot
      Q8VCV0, Q9D665
      Related
      ENSMUSP00000044457.8, ENSMUST00000037955.14
      Conserved Domains (1) summary
      cl21454
      Location:10351
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      118388138..118400428 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006531409.3XP_006531472.1  short-chain dehydrogenase/reductase family 42E member 1 isoform X1

      UniProtKB/Swiss-Prot
      Q8VCV0, Q9D665
      Conserved Domains (1) summary
      cl21454
      Location:10351
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins