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    Tceal8 transcription elongation factor A (SII)-like 8 [ Mus musculus (house mouse) ]

    Gene ID: 66684, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Tceal8provided by MGI
    Official Full Name
    transcription elongation factor A (SII)-like 8provided by MGI
    Primary source
    MGI:MGI:1913934
    See related
    Ensembl:ENSMUSG00000051579 AllianceGenome:MGI:1913934
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    3930402F23Rik
    Summary
    Predicted to be located in nucleus. Is expressed in several structures, including ganglia; genitourinary system; gut; limb; and sensory organ. Orthologous to human TCEAL8 (transcription elongation factor A like 8). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in placenta adult (RPKM 40.4), liver E14 (RPKM 36.2) and 14 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Tceal8 in Genome Data Viewer
    Location:
    X F1; X 57.4 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (135069733..135073000, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (136168984..136172251, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene nuclear RNA export factor 3 Neighboring gene RIKEN cDNA 5730412P04 gene Neighboring gene brain expressed X-linked 4 Neighboring gene microRNA 6383 Neighboring gene predicted gene, 41901 Neighboring gene nuclear encoded tRNA lysine 19 (anticodon CTT)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Defined factors to reactivate cell cycle activity in adult mouse cardiomyocytes. Judd J, et al. Sci Rep, 2019 Dec 11. PMID 31827131, Free PMC Article
    2. Interaction between nucleosome assembly protein 1-like family members. Attia M, et al. J Mol Biol, 2011 Apr 15. PMID 21333655
    3. Characterization of an eutherian gene cluster generated after transposon domestication identifies Bex3 as relevant for advanced neurological functions. Navas-Pérez E, et al. Genome Biol, 2020 Oct 26. PMID 33100228, Free PMC Article
    4. A 1.1-Mb segmental deletion on the X chromosome causes meiotic failure in male mice. Zhou J, et al. Biol Reprod, 2013 Jun. PMID 23677977, Free PMC Article
    5. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Defined factors to reactivate cell cycle activity in adult mouse cardiomyocytes.
      Title: Defined factors to reactivate cell cycle activity in adult mouse cardiomyocytes.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transcription elongation factor A protein-like 8
    Names
    TCEA-like protein 8
    transcription elongation factor S-II protein-like 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001168578.1 → NP_001162050.1  transcription elongation factor A protein-like 8

      See identical proteins and their annotated locations for NP_001162050.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AL772180
      Consensus CDS
      CCDS30415.1
      UniProtKB/Swiss-Prot
      A2AJR7, Q9CYP9, Q9CZY2
      Related
      ENSMUSP00000129591.2, ENSMUST00000163584.8
      Conserved Domains (1) summary
      pfam04538
      Location:1 → 113
      BEX; Brain expressed X-linked like family

    2. NM_025703.3 → NP_079979.2  transcription elongation factor A protein-like 8

      See identical proteins and their annotated locations for NP_079979.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AA867696, AK076203, AK083347
      Consensus CDS
      CCDS30415.1
      UniProtKB/Swiss-Prot
      A2AJR7, Q9CYP9, Q9CZY2
      Related
      ENSMUSP00000056189.4, ENSMUST00000060101.10
      Conserved Domains (1) summary
      pfam04538
      Location:1 → 113
      BEX; Brain expressed X-linked like family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      135069733..135073000 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9CZY2.1 GenPept UniProtKB/Swiss-Prot:Q9CZY2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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