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    putative hydrolase [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853833, updated on 9-Dec-2024

    Summary

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    Official Full Name
    putative hydrolase
    Primary source
    SGD:S000007242
    Locus tag
    YKL033W-A
    See related
    AllianceGenome:SGD:S000007242; FungiDB:YKL033W-A; VEuPathDB:YKL033W-A
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables 5'-nucleotidase activity and pseudouridine 5'-phosphatase activity. Orthologous to human PUDP (pseudouridine 5'-phosphatase). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    Location:
    chromosome: XI
    Exon count:
    1
    Sequence:
    Chromosome: XI; NC_001143.9 (374505..375215)

    Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene UTP glucose-1-phosphate uridylyltransferase Neighboring gene ubiquitin-protein ligase TUL1 Neighboring gene Tti1p Neighboring gene tRNA-Val

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001143.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional Diversity of Haloacid Dehalogenase Superfamily Phosphatases from Saccharomyces cerevisiae: BIOCHEMICAL, STRUCTURAL, AND EVOLUTIONARY INSIGHTS. Kuznetsova E, et al. J Biol Chem, 2015 Jul 24. PMID 26071590, Free PMC Article
    2. Mass-murdering: deletion of twenty-three ORFs from Saccharomyces cerevisiae chromosome XI reveals five genes essential for growth and three genes conferring detectable mutant phenotype. Wysocki R, et al. Gene, 1999 Mar 18. PMID 10095102
    3. Enrichment-Based Proteogenomics Identifies Microproteins, Missing Proteins, and Novel smORFs in Saccharomyces cerevisiae. He C, et al. J Proteome Res, 2018 Jul 6. PMID 29897761
    4. A proteomic screen of Ty1 integrase partners identifies the protein kinase CK2 as a regulator of Ty1 retrotransposition. Barkova A, et al. Mob DNA, 2022 Nov 18. PMID 36401307, Free PMC Article
    5. Complete DNA sequence of yeast chromosome XI. Dujon B, et al. Nature, 1994 Jun 2. PMID 8196765

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables 5'-nucleotidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables XMP 5'-nucleosidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pseudouridine 5'-phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables pseudouridine 5'-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    putative hydrolase
    NP_012891.4
    • hypothetical protein; similar to uncharacterized proteins from other fungi

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001143.9 Reference assembly

      Range
      374505..375215
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184335.3 → NP_012891.4  TPA: putative hydrolase [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012891.4

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VXQ2, Q86ZR7
      UniProtKB/TrEMBL
      A6ZZT1, B3LR53, C7GP39, C8ZCD6, G2WHZ7, N1P2F6
      Conserved Domains (1) summary
      cd07529
      Location:7 → 202
      HAD_AtGPP-like; subfamily of beta-phosphoglucomutase-like family, similar to Arabidopsis thaliana Gpp1 and Gpp2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q86ZR7.2

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