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    RPL16A ribosomal 60S subunit protein L16A [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854673, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RPL16A
    Official Full Name
    ribosomal 60S subunit protein L16A
    Primary source
    SGD:S000001395
    Locus tag
    YIL133C
    See related
    AllianceGenome:SGD:S000001395; FungiDB:YIL133C; VEuPathDB:YIL133C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    RPL13
    Summary
    Enables RNA binding activity. Involved in maturation of LSU-rRNA. Part of cytosolic large ribosomal subunit. Is active in nucleolus. Orthologous to human RPL13A (ribosomal protein L13a). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See RPL16A in Genome Data Viewer
    Location:
    chromosome: IX
    Exon count:
    2
    Sequence:
    Chromosome: IX; NC_001141.2 (98527..99416, complement)

    Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene flavin adenine dinucleotide transporter FLX1 Neighboring gene Csm2p Neighboring gene forkhead family transcription factor FKH1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001141.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Role of the yeast ribosomal protein L16 in ribosome biogenesis. Espinar-Marchena FJ, et al. FEBS J, 2016 Aug. PMID 27374275
    2. Ribosomal protein L14 contributes to the early assembly of 60S ribosomal subunits in Saccharomyces cerevisiae. Espinar-Marchena F, et al. Nucleic Acids Res, 2018 May 18. PMID 29788267, Free PMC Article
    3. Vanillin inhibits translation and induces messenger ribonucleoprotein (mRNP) granule formation in saccharomyces cerevisiae: application and validation of high-content, image-based profiling. Iwaki A, et al. PLoS One, 2013. PMID 23637899, Free PMC Article
    4. Association of RAP1 binding sites with stringent control of ribosomal protein gene transcription in Saccharomyces cerevisiae. Moehle CM, et al. Mol Cell Biol, 1991 May. PMID 2017175, Free PMC Article
    5. Affinity purification of ribosomes to access the translatome. Halbeisen RE, et al. Methods, 2009 Jul. PMID 19398006

    See all (143) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables RNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IC
    Inferred by Curator
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in maturation of LSU-rRNA IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of large ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal 60S subunit protein L16A
    NP_012133.1
    • Ribosomal 60S subunit protein L16A; N-terminally acetylated, binds 5.8 S rRNA; transcriptionally regulated by Rap1p; homologous to mammalian ribosomal protein L13A and bacterial L13; RPL16A has a paralog, RPL16B, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001141.2 Reference assembly

      Range
      98527..99416 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179481.1 → NP_012133.1  TPA: ribosomal 60S subunit protein L16A [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012133.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VVF4, P26784
      UniProtKB/TrEMBL
      A6ZVE3, B3LTY0, C8ZAY1, G2WG18, N1P0T6
      Conserved Domains (1) summary
      PTZ00068
      Location:6 → 199
      PTZ00068; 60S ribosomal protein L13a; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P26784.3

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