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    SDS23 Sds23p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852824, updated on 9-Dec-2024

    Summary

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    Official Symbol
    SDS23
    Official Full Name
    Sds23p
    Primary source
    SGD:S000003024
    Locus tag
    YGL056C
    See related
    AllianceGenome:SGD:S000003024; FungiDB:YGL056C; VEuPathDB:YGL056C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable protein serine/threonine phosphatase inhibitor activity. Involved in septum digestion after cytokinesis. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See SDS23 in Genome Data Viewer
    Location:
    chromosome: VII
    Exon count:
    1
    Sequence:
    Chromosome: VII; NC_001139.9 (396035..397618, complement)

    Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene E2 ubiquitin-conjugating protein RAD6 Neighboring gene Gep7p Neighboring gene stearoyl-CoA 9-desaturase Neighboring gene cornichon family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001139.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional conservation between fission yeast moc1/sds23 and its two orthologs, budding yeast SDS23 and SDS24, and phenotypic differences in their disruptants. Goldar MM, et al. Biosci Biotechnol Biochem, 2005 Jul. PMID 16041152
    2. Identification of novel genes to assign enhanced tolerance to osmotic stress in Saccharomyces cerevisiae. Kim B, et al. FEMS Microbiol Lett, 2018 Jul 1. PMID 29931330
    3. Identification of phosphatase 2A-like Sit4-mediated signalling and ubiquitin-dependent protein sorting as modulators of caffeine sensitivity in S. cerevisiae. Hood-DeGrenier JK. Yeast, 2011 Mar. PMID 21360731
    4. SAC3 may link nuclear protein export to cell cycle progression. Jones AL, et al. Proc Natl Acad Sci U S A, 2000 Mar 28. PMID 10716708, Free PMC Article
    5. Physiological effects of unassembled chaperonin Cct subunits in the yeast Saccharomyces cerevisiae. Kabir MA, et al. Yeast, 2005 Feb. PMID 15704212

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables protein serine/threonine phosphatase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cellular response to glucose starvation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cellular response to glucose starvation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of mitotic metaphase/anaphase transition IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in septum digestion after cytokinesis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Sds23p
    NP_011459.2
    • Protein involved in cell separation during budding; one of two S. cerevisiae homologs (Sds23p and Sds24p) of the S. pombe Sds23 protein, which is implicated in APC/cyclosome regulation; SDS23 has a paralog, SDS24, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001139.9 Reference assembly

      Range
      396035..397618 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180921.2 → NP_011459.2  TPA: Sds23p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011459.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VU85, P53172, Q6B1R7
      UniProtKB/TrEMBL
      G2WE41, N1P9R5
      Conserved Domains (2) summary
      smart00116
      Location:276 → 322
      CBS; Domain in cystathionine beta-synthase and other proteins
      cd02205
      Location:190 → 259
      CBS_pair_SF; CBS repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53172.2

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