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    YFH7 Yfh7p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850558, updated on 9-Dec-2024

    Summary

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    Official Symbol
    YFH7
    Official Full Name
    Yfh7p
    Primary source
    SGD:S000001903
    Locus tag
    YFR007W
    See related
    AllianceGenome:SGD:S000001903; FungiDB:YFR007W; VEuPathDB:YFR007W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    AIM12
    Summary
    Enables ATP hydrolysis activity. Predicted to be involved in phosphorylation. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See YFH7 in Genome Data Viewer
    Location:
    chromosome: VI
    Exon count:
    1
    Sequence:
    Chromosome: VI; NC_001138.5 (159299..160360)

    Chromosome VI - NC_001138.5Genomic Context describing neighboring genes Neighboring gene putative Xaa-Pro dipeptidase Neighboring gene tRNA-Phe Neighboring gene Far7p Neighboring gene tRNA-Gly

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001138.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Crystal structure and functional analysis identify the P-loop containing protein YFH7 of Saccharomyces cerevisiae as an ATP-dependent kinase. Gueguen-Chaignon V, et al. Proteins, 2008 May 1. PMID 18004758
    2. Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae. Murakami Y, et al. Nat Genet, 1995 Jul. PMID 7670463
    3. Diverse cellular functions of the Hsp90 molecular chaperone uncovered using systems approaches. McClellan AJ, et al. Cell, 2007 Oct 5. PMID 17923092
    4. A comprehensive two-hybrid analysis to explore the yeast protein interactome. Ito T, et al. Proc Natl Acad Sci U S A, 2001 Apr 10. PMID 11283351, Free PMC Article
    5. Pervasive and dynamic protein binding sites of the mRNA transcriptome in Saccharomyces cerevisiae. Freeberg MA, et al. Genome Biol, 2013 Feb 14. PMID 23409723, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in phosphorylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Yfh7p
    NP_116662.1
    • Putative kinase with similarity to the PRK/URK/PANK kinase subfamily; the PRK/URK/PANK subfamily of P-loop kinases is also known as phosphoribulokinase/uridine kinase/bacterial pantothenate kinase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001138.5 Reference assembly

      Range
      159299..160360
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179972.1 → NP_116662.1  TPA: Yfh7p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_116662.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VTN7, P43591
      UniProtKB/TrEMBL
      G2WDE6
      Conserved Domains (1) summary
      COG1072
      Location:21 → 353
      CoaA; Panthothenate kinase [Coenzyme transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P43591.1

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