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    PET18 Pet18p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850382, updated on 9-Dec-2024

    Summary

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    Official Symbol
    PET18
    Official Full Name
    Pet18p
    Primary source
    SGD:S000000613
    Locus tag
    YCR020C
    See related
    AllianceGenome:SGD:S000000613; FungiDB:YCR020C; VEuPathDB:YCR020C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    HIT2
    Summary
    Involved in thiamine metabolic process. Located in cytosol. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See PET18 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_001135.5 (154012..154659, complement)

    Chromosome III - NC_001135.5Genomic Context describing neighboring genes Neighboring gene tRNA-Lys Neighboring gene Mak32p Neighboring gene Mak31p Neighboring gene Htl1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001135.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The PET18 locus of Saccharomyces cerevisiae: a complex locus containing multiple genes. Toh-e A, et al. Yeast, 1985 Dec. PMID 3916862
    2. Molecular analysis of a Saccharomyces cerevisiae mutant with improved ability to utilize xylose shows enhanced expression of proteins involved in transport, initial xylose metabolism, and the pentose phosphate pathway. Wahlbom CF, et al. Appl Environ Microbiol, 2003 Feb. PMID 12570990, Free PMC Article
    3. Ty element-induced temperature-sensitive mutations of Saccharomyces cerevisiae. Kawakami K, et al. Genetics, 1992 Aug. PMID 1325386, Free PMC Article
    4. Genetic redundancy and gene fusion in the genome of the Baker's yeast Saccharomyces cerevisiae: functional characterization of a three-member gene family involved in the thiamine biosynthetic pathway. Llorente B, et al. Mol Microbiol, 1999 Jun. PMID 10383756
    5. Dissecting the pet18 mutation in Saccharomyces cerevisiae: HTL1 encodes a 7-kDa polypeptide that interacts with components of the RSC complex. Lu YM, et al. Mol Genet Genomics, 2003 Jun. PMID 12684875

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in thiamine metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in thiamine metabolic process IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Pet18p
    NP_009947.1
    • hypothetical protein; has weak similarity to proteins involved in thiamin metabolism; expression is induced in the absence of thiamin

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001135.5 Reference assembly

      Range
      154012..154659 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178733.1 → NP_009947.1  TPA: Pet18p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009947.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VR28, P25362
      UniProtKB/TrEMBL
      A6ZTK0, B3LU90, C7GW77, C8Z4A8, G2WA36, N1PAQ1
      Conserved Domains (1) summary
      cd19358
      Location:4 → 213
      TenA_E_Spr0628-like; TenA_E proteins similar to Streptococcus pneumoniae Spr0628 and Saccharomyces cerevisiae S288C PET18
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P25362.1

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