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    CMR3 Cmr3p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856123, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CMR3
    Official Full Name
    Cmr3p
    Primary source
    SGD:S000006217
    Locus tag
    YPR013C
    See related
    AllianceGenome:SGD:S000006217; FungiDB:YPR013C; VEuPathDB:YPR013C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables DNA binding activity. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 1K and osteogenesis imperfecta type 12. Orthologous to human SP6 (Sp6 transcription factor) and SP7 (Sp7 transcription factor). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See CMR3 in Genome Data Viewer
    Location:
    chromosome: XVI
    Exon count:
    1
    Sequence:
    Chromosome: XVI; NC_001148.4 (584632..585585, complement)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene Mra1p Neighboring gene Mrx21p Neighboring gene uncharacterized protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001148.4

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcriptome profiling of Saccharomyces cerevisiae mutants lacking C2H2 zinc finger proteins. Mao J, et al. BMC Genomics, 2008. PMID 18366603, Free PMC Article
    2. Massively parallel measurements of molecular interaction kinetics on a microfluidic platform. Geertz M, et al. Proc Natl Acad Sci U S A, 2012 Oct 9. PMID 23012409, Free PMC Article
    3. High-resolution DNA-binding specificity analysis of yeast transcription factors. Zhu C, et al. Genome Res, 2009 Apr. PMID 19158363, Free PMC Article
    4. Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome. Finch AJ, et al. Genes Dev, 2011 May 1. PMID 21536732, Free PMC Article
    5. Variations of the C2H2 zinc finger motif in the yeast genome and classification of yeast zinc finger proteins. Böhm S, et al. Nucleic Acids Res, 1997 Jun 15. PMID 9171100, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding HDA PubMed 
    enables zinc ion binding RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Cmr3p
    NP_015338.1
    • Putative zinc finger protein; YPR013C is not an essential gene

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      584632..585585 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184110.1 → NP_015338.1  TPA: Cmr3p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015338.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W424, Q12145
      UniProtKB/TrEMBL
      A6ZWQ7, B3LL73, C7GV38, N1NW03
      Conserved Domains (2) summary
      COG5048
      Location:17 → 316
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00019
      Location:256 → 276
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12145.1

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