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    HER1 Her1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854402, updated on 9-Dec-2024

    Summary

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    Official Symbol
    HER1
    Official Full Name
    Her1p
    Primary source
    SGD:S000005753
    Locus tag
    YOR227W
    See related
    AllianceGenome:SGD:S000005753; FungiDB:YOR227W; VEuPathDB:YOR227W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in endoplasmic reticulum organization. Located in mitochondrion. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See HER1 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (762825..766565)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene DNA-directed RNA polymerase core subunit RPB8 Neighboring gene putative iron-binding protein ISU2 Neighboring gene Mcp1p Neighboring gene transcriptional modulator

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and structural analysis of Hmg2p-induced endoplasmic reticulum remodeling in Saccharomyces cerevisiae. Federovitch CM, et al. Mol Biol Cell, 2008 Oct. PMID 18667535, Free PMC Article
    2. Bayesian Markov Random Field analysis for protein function prediction based on network data. Kourmpetis YA, et al. PLoS One, 2010 Feb 24. PMID 20195360, Free PMC Article
    3. A large-scale overexpression screen in Saccharomyces cerevisiae identifies previously uncharacterized cell cycle genes. Stevenson LF, et al. Proc Natl Acad Sci U S A, 2001 Mar 27. PMID 11274415, Free PMC Article
    4. TORC2-dependent protein kinase Ypk1 phosphorylates ceramide synthase to stimulate synthesis of complex sphingolipids. Muir A, et al. Elife, 2014 Oct 3. PMID 25279700, Free PMC Article
    5. Novel interactions of Saccharomyces cerevisiae type 1 protein phosphatase identified by single-step affinity purification and mass spectrometry. Walsh EP, et al. Biochemistry, 2002 Feb 19. PMID 11841235

    See all (45) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum organization IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 

    General protein information

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    Preferred Names
    Her1p
    NP_014870.1
    • hypothetical protein; required for proliferation or remodeling of the ER that is caused by overexpression of Hmg2p; may interact with ribosomes, based on co-purification experiments; HER1 has a paralog, GIP3, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      762825..766565
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183646.1 → NP_014870.1  TPA: Her1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014870.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W2T1, Q12276
      UniProtKB/TrEMBL
      C7GWF7
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12276.1

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