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    nucleotide diphosphatase [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854278, updated on 9-Dec-2024

    Summary

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    Official Full Name
    nucleotide diphosphatase
    Primary source
    SGD:S000005637
    Locus tag
    YOR111W
    See related
    AllianceGenome:SGD:S000005637; FungiDB:YOR111W; VEuPathDB:YOR111W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable nucleoside triphosphate diphosphatase activity. Predicted to be involved in nucleotide metabolic process. Predicted to be located in cytoplasm. Orthologous to human ASMTL (acetylserotonin O-methyltransferase like). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (530429..531127)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene phosphatidylinositol-3-/phosphoinositide 5-phosphatase INP53 Neighboring gene transcription factor TFIIIC subunit TFC7 Neighboring gene Cex1p Neighboring gene Azf1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A genomic analysis of chronological longevity factors in budding yeast. Burtner CR, et al. Cell Cycle, 2011 May 1. PMID 21447998, Free PMC Article
    2. A Comprehensive Analysis of Replicative Lifespan in 4,698 Single-Gene Deletion Strains Uncovers Conserved Mechanisms of Aging. McCormick MA, et al. Cell Metab, 2015 Nov 3. PMID 26456335, Free PMC Article
    3. The ubiquitin-proteasome system regulates meiotic chromosome organization. Yang X, et al. Proc Natl Acad Sci U S A, 2022 Apr 26. PMID 35439061, Free PMC Article
    4. The nucleotide sequence of Saccharomyces cerevisiae chromosome XV. Dujon B, et al. Nature, 1997 May 29. PMID 9169874
    5. Biochemical and structural studies of conserved Maf proteins revealed nucleotide pyrophosphatases with a preference for modified nucleotides. Tchigvintsev A, et al. Chem Biol, 2013 Nov 21. PMID 24210219, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables 8-oxo-(d)RTP hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables UTP diphosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables dTTP diphosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables nucleoside triphosphate diphosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables nucleoside triphosphate diphosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in nucleotide metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    nucleotide diphosphatase
    NP_014754.3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      530429..531127
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183530.3 → NP_014754.3  TPA: nucleotide diphosphatase [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014754.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W2H0, Q99210
      UniProtKB/TrEMBL
      B3LJF4, B5VS01, C7GMM5, G2WMY7, N1NYE6
      Conserved Domains (1) summary
      TIGR00172
      Location:17 → 226
      maf; MAF protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q99210.1

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