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    RPS7A ribosomal 40S subunit protein S7A [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854263, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RPS7A
    Official Full Name
    ribosomal 40S subunit protein S7A
    Primary source
    SGD:S000005622
    Locus tag
    YOR096W
    See related
    AllianceGenome:SGD:S000005622; FungiDB:YOR096W; VEuPathDB:YOR096W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    RPS30
    Summary
    Predicted to be a structural constituent of ribosome. Involved in ribosome biogenesis. Part of small-subunit processome. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 8. Orthologous to human RPS7 (ribosomal protein S7). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See RPS7A in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    2
    Sequence:
    Chromosome: XV; NC_001147.6 (505794..506767)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Arf family GTPase ARF3 Neighboring gene ribose-5-phosphate isomerase RKI1 Neighboring gene uncharacterized protein Neighboring gene FG-nucleoporin NUP1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The yeast ribosomal protein S7 and its genes. Synetos D, et al. J Biol Chem, 1992 Feb 15. PMID 1737755
    2. Ribosomal protein S7 ubiquitination during ER stress in yeast is associated with selective mRNA translation and stress outcome. Matsuki Y, et al. Sci Rep, 2020 Nov 12. PMID 33184379, Free PMC Article
    3. SIR2-induced inviability is suppressed by histone H4 overexpression. Matecic M, et al. Genetics, 2002 Oct. PMID 12399404, Free PMC Article
    4. Structure of the no-go mRNA decay complex Dom34-Hbs1 bound to a stalled 80S ribosome. Becker T, et al. Nat Struct Mol Biol, 2011 Jun. PMID 21623367
    5. Presence of Not5 and ubiquitinated Rps7A in polysome fractions depends upon the Not4 E3 ligase. Panasenko OO, et al. Mol Microbiol, 2012 Feb. PMID 22243599

    See all (121) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytoplasmic translation NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in rRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in ribosomal small subunit biogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in ribosome biogenesis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of 90S preribosome HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic small ribosomal subunit NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of small-subunit processome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of small-subunit processome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ribosomal 40S subunit protein S7A
    NP_014739.1
    • Protein component of the small (40S) ribosomal subunit; interacts with Kti11p; deletion causes hypersensitivity to zymocin; homologous to mammalian ribosomal protein S7, no bacterial homolog; RPS7A has a paralog, RPS7B, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      505794..506767
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183515.1 → NP_014739.1  TPA: ribosomal 40S subunit protein S7A [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014739.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W2F7, P26786, Q08502
      UniProtKB/TrEMBL
      A6ZNU6, B3LJE2, C7GMN8, C8ZI57, G2WMX3, N1NYD4
      Conserved Domains (1) summary
      pfam01251
      Location:6 → 186
      Ribosomal_S7e; Ribosomal protein S7e
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P26786.4

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