U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    SFM1 protein-arginine N-methyltransferase SFM1 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854186, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    SFM1
    Official Full Name
    protein-arginine N-methyltransferase SFM1
    Primary source
    SGD:S000005547
    Locus tag
    YOR021C
    See related
    AllianceGenome:SGD:S000005547; FungiDB:YOR021C; VEuPathDB:YOR021C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables protein-arginine omega-N monomethyltransferase activity. Involved in peptidyl-arginine methylation. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See SFM1 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (372798..373439, complement)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Hsp10p Neighboring gene Mco10p Neighboring gene putative carboxylic ester hydrolase Neighboring gene Ahc1p

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Probabilistic protein function prediction from heterogeneous genome-wide data. Nariai N, et al. PLoS One, 2007 Mar 28. PMID 17396164, Free PMC Article
    2. Structural basis for Sfm1 functioning as a protein arginine methyltransferase. Lv F, et al. Cell Discov, 2015. PMID 27462434, Free PMC Article
    3. Identification of methylated proteins in the yeast small ribosomal subunit: a role for SPOUT methyltransferases in protein arginine methylation. Young BD, et al. Biochemistry, 2012 Jun 26. PMID 22650761, Free PMC Article
    4. Ribosomal protein methyltransferases in the yeast Saccharomyces cerevisiae: Roles in ribosome biogenesis and translation. Al-Hadid Q, et al. Biochem Biophys Res Commun, 2016 Feb 12. PMID 26801560, Free PMC Article
    5. The budding yeast rRNA and ribosome biosynthesis (RRB) regulon contains over 200 genes. Wade CH, et al. Yeast, 2006 Mar. PMID 16544271

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-arginine omega-N monomethyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein-arginine omega-N monomethyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in peptidyl-arginine methylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    protein-arginine N-methyltransferase SFM1
    NP_014664.1
    • SPOUT methyltransferase; catalyzes omega-monomethylation of Rps3p on Arg-146; not an essential gene; predicted to be involved in rRNA processing and ribosome biogenesis and in biopolymer catabolism

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      372798..373439 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183440.1 → NP_014664.1  TPA: protein-arginine N-methyltransferase SFM1 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014664.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W288, Q12314
      UniProtKB/TrEMBL
      A6ZNM6, B3LJ76, B5VRS4, C7GLF2, C8ZHY4, G2WMQ3, N1NWU1
      Conserved Domains (1) summary
      pfam04252
      Location:2 → 206
      RNA_Me_trans; Predicted SAM-dependent RNA methyltransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12314.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools