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    ADD37 Add37p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855222, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ADD37
    Official Full Name
    Add37p
    Primary source
    SGD:S000004796
    Locus tag
    YMR184W
    See related
    AllianceGenome:SGD:S000004796; FungiDB:YMR184W; VEuPathDB:YMR184W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in ERAD pathway. Located in cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ADD37 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (628189..628785)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene syntaxin Neighboring gene Rtp1p Neighboring gene Hsp90 family chaperone HSC82

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Differential requirements of novel A1PiZ degradation deficient (ADD) genes in ER-associated protein degradation. Palmer EA, et al. J Cell Sci, 2003 Jun 1. PMID 12711700
    2. Substrate specificity analysis of protein kinase complex Dbf2-Mob1 by peptide library and proteome array screening. Mah AS, et al. BMC Biochem, 2005 Oct 21. PMID 16242037, Free PMC Article
    3. Global protein expression profiling of budding yeast in response to DNA damage. Lee MW, et al. Yeast, 2007 Mar. PMID 17351896
    4. Dosage suppression genetic interaction networks enhance functional wiring diagrams of the cell. Magtanong L, et al. Nat Biotechnol, 2011 May 15. PMID 21572441, Free PMC Article
    5. Functional profiling of the Saccharomyces cerevisiae genome. Giaever G, et al. Nature, 2002 Jul 25. PMID 12140549

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in ERAD pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Add37p
    NP_013909.1
    • hypothetical protein; involved in ER-associated protein degradation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and is induced in response to the DNA-damaging agent MMS; YMR184W is not an essential gene; protein abundance increases in response to DNA replication stress

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      628189..628785
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182690.1 → NP_013909.1  TPA: Add37p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013909.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W008, Q03233
      UniProtKB/TrEMBL
      G2WKN9, N1NXI2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q03233.1

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