Apobr apolipoprotein B receptor [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Apobrprovided by MGI
Official Full Name: apolipoprotein B receptorprovided by MGI
Primary source: MGI:MGI:2176230
See related: Ensembl:ENSMUSG00000042759 AllianceGenome:MGI:2176230
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Apob48r; Apob-48r
Summary: Enables very-low-density lipoprotein particle receptor activity. Acts upstream of or within triglyceride metabolic process. Predicted to be located in plasma membrane. Predicted to be part of chylomicron; low-density lipoprotein particle; and very-low-density lipoprotein particle. Orthologous to human APOBR (apolipoprotein B receptor). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Broad expression in placenta adult (RPKM 11.1), genital fat pad adult (RPKM 7.1) and 15 other tissues See more
Orthologs: human all
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Genomic context

Location:: 7 F3; 7 69.17 cM

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (126184092..126188297)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (126584918..126589125)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

NoName (e-PCR)
- UniSTS:235779

Apob48r-pending (e-PCR), detects polymorphism
- UniSTS:254233

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables very-low-density lipoprotein particle receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables very-low-density lipoprotein particle receptor activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in cholesterol metabolic process	IEA Inferred from Electronic Annotation more info
involved_in lipid transport	IEA Inferred from Electronic Annotation more info
involved_in triglyceride metabolic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within triglyceride metabolic process	IDA Inferred from Direct Assay more info	PubMed
involved_in vesicle-mediated transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of chylomicron	IEA Inferred from Electronic Annotation more info
part_of low-density lipoprotein particle	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
part_of very-low-density lipoprotein particle	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: apolipoprotein B receptor

Names: apolipoprotein B-100 receptor; apolipoprotein B-48 receptor; apolipoprotein B48 receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_138310.1 → NP_612183.1 apolipoprotein B receptor

See identical proteins and their annotated locations for NP_612183.1

Status: PROVISIONAL

Source sequence(s)

AF141335

Consensus CDS

CCDS21834.1

UniProtKB/Swiss-Prot

Q8VBT6

Related

ENSMUSP00000042028.7, ENSMUST00000039522.8

Conserved Domains (2) summary

PTZ00121
Location:32 → 475

PTZ00121; MAEBL; Provisional

TIGR00927
Location:503 → 804

2A1904; K+-dependent Na+/Ca+ exchanger

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000073.7 Reference GRCm39 C57BL/6J

Range

126184092..126188297

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_036152727.1 → XP_036008620.1 apolipoprotein B receptor isoform X1

Conserved Domains (2) summary

PTZ00121
Location:32 → 475

PTZ00121; MAEBL; Provisional

TIGR00927
Location:503 → 804

2A1904; K+-dependent Na+/Ca+ exchanger
XM_006507399.5 → XP_006507462.1 apolipoprotein B receptor isoform X3

Conserved Domains (1) summary

PTZ00121
Location:32 → 475

PTZ00121; MAEBL; Provisional
XM_036152728.1 → XP_036008621.1 apolipoprotein B receptor isoform X2

Conserved Domains (1) summary

PTZ00121
Location:32 → 475

PTZ00121; MAEBL; Provisional
XM_036152729.1 → XP_036008622.1 apolipoprotein B receptor isoform X4
XM_036152730.1 → XP_036008623.1 apolipoprotein B receptor isoform X5