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    Slco4c1 solute carrier organic anion transporter family, member 4C1 [ Mus musculus (house mouse) ]

    Gene ID: 227394, updated on 27-Nov-2024

    Summary

    Official Symbol
    Slco4c1provided by MGI
    Official Full Name
    solute carrier organic anion transporter family, member 4C1provided by MGI
    Primary source
    MGI:MGI:2442784
    See related
    Ensembl:ENSMUSG00000040693 AllianceGenome:MGI:2442784
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    OATPX; OATP-H; oatp-R; OATP-M1; OATP4C1; PRO2176; SLC21A20; 9530051F04; C330017E21Rik
    Summary
    Predicted to enable sodium-independent organic anion transmembrane transporter activity. Predicted to be involved in sodium-independent organic anion transport. Predicted to be active in basolateral plasma membrane. Is expressed in several structures, including forebrain; genitourinary system; integumental system; respiratory system; and sensory organ. Orthologous to human SLCO4C1 (solute carrier organic anion transporter family member 4C1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in genital fat pad adult (RPKM 3.6), lung adult (RPKM 3.6) and 8 other tissues See more
    Orthologs
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    Genomic context

    See Slco4c1 in Genome Data Viewer
    Location:
    1 D; 1 47.76 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (96744918..96800027, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (96816270..96872193, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930533P14 gene Neighboring gene abhydrolase domain containing 6 pseudogene Neighboring gene STARR-seq mESC enhancer starr_01769 Neighboring gene predicted gene, 26078 Neighboring gene STARR-seq mESC enhancer starr_01771 Neighboring gene STARR-seq mESC enhancer starr_01772 Neighboring gene pluripotency-associated noncoding transcript 2 Neighboring gene solute carrier organic anion transporter family, member 6b1 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables organic anion transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables organic anion transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables sodium-independent organic anion transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within organic anion transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in organic anion transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in sodium-independent organic anion transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in spermatogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in basolateral plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in basolateral plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    solute carrier organic anion transporter family member 4C1
    Names
    organic anion transporting polypeptide 4C1
    solute carrier family 21 member 20

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172658.3NP_766246.1  solute carrier organic anion transporter family member 4C1

      See identical proteins and their annotated locations for NP_766246.1

      Status: PROVISIONAL

      Source sequence(s)
      AK049253
      Consensus CDS
      CCDS35675.1
      UniProtKB/Swiss-Prot
      Q8BGD4
      Related
      ENSMUSP00000071875.5, ENSMUST00000071985.6
      Conserved Domains (3) summary
      cd06174
      Location:120473
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      cd01330
      Location:496549
      KAZAL_SLC21; The kazal-type serine protease inhibitor domain has been detected in an extracellular loop region of solute carrier 21 (SLC21) family members (organic anion transporters) , which may regulate the specificity of anion uptake. The KAZAL_SLC21 domain is a ...
      pfam03137
      Location:102662
      OATP; Organic Anion Transporter Polypeptide (OATP) family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      96744918..96800027 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_001784188.3 RNA Sequence