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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001305663.1 → NP_001292592.1 protein THEMIS isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) uses an alternate 5' exon and lacks a 3' coding exon compared to variant 1. This variant represents translation initiation at a downstream AUG compared to variant 1; the 5'-most initiation codon, as used in variant 1, is associated with a truncated ORF that would render the transcript a candidate for nonsense-mediated decay (NMD). The encoded isoform (2) has a shorter N-terminus and a shorter and distinct C-terminus, compared to isoform 1.
- Source sequence(s)
-
AC153798, AC159472, AK040594, AK169558, BB638055
- UniProtKB/Swiss-Prot
-
Q8BGW0
- Conserved Domains (1) summary
-
- pfam12736
Location:1 → 177
- CABIT; Cell-cycle sustaining, positive selection,
-
NM_001374699.1 → NP_001361628.1 protein THEMIS isoform 4
Status: REVIEWED
- Source sequence(s)
-
AC152983, AC159472
- Consensus CDS
-
CCDS87977.1
- Related
- ENSMUSP00000101155.3, ENSMUST00000105516.9
- Conserved Domains (1) summary
-
- pfam12736
Location:17 → 266
- CABIT; Cell-cycle sustaining, positive selection,
-
NM_178666.6 → NP_848781.1 protein THEMIS isoform 1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
- Source sequence(s)
-
AA967480, AK040594, AK169558, BB638055
- Consensus CDS
-
CCDS23758.1
- UniProtKB/Swiss-Prot
- Q059Y0, Q3TEM0, Q3UU76, Q8BGP0, Q8BGW0, Q8C9S6
- Related
- ENSMUSP00000060129.5, ENSMUST00000056097.11
- Conserved Domains (1) summary
-
- pfam12736
Location:17 → 266
- CABIT; Cell-cycle sustaining, positive selection,
RNA
-
NR_131208.1 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) has multiple differences, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AC152983, AC159472
- Related
-
ENSMUST00000162202.8
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCm39 C57BL/6J
Genomic
-
NC_000076.7 Reference GRCm39 C57BL/6J
- Range
-
28544356..28759816
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_006512643.1 → XP_006512706.1 protein THEMIS isoform X1
- Conserved Domains (1) summary
-
- pfam12736
Location:1 → 177
- CABIT; Cell-cycle sustaining, positive selection,