Tas2r118 taste receptor, type 2, member 118 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Tas2r118provided by MGI
Official Full Name: taste receptor, type 2, member 118provided by MGI
Primary source: MGI:MGI:2681247
See related: Ensembl:ENSMUSG00000043865 AllianceGenome:MGI:2681247
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Gm465; T2R16; T2R18; mGR18; mt2r40; Tas2r16; Tas2r18
Summary: Predicted to enable bitter taste receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of bitter taste. Predicted to be located in endoplasmic reticulum; external side of plasma membrane; and trans-Golgi network. Predicted to be active in membrane. Is expressed in circumvallate papillae; colon; and jejunum. Human ortholog(s) of this gene implicated in alcohol dependence. Orthologous to human TAS2R16 (taste 2 receptor member 16). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human all
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Genomic context

Location:: 6 A3.1; 6 11.18 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	6	NC_000072.7 (23969160..23970059, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	6	NC_000072.6 (23969161..23970060, complement)

Chromosome 6 - NC_000072.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

NoName (e-PCR)
- UniSTS:493143

NoName (e-PCR)
- UniSTS:490633

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables bitter taste receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables bitter taste receptor activity	IEA Inferred from Electronic Annotation more info
enables bitter taste receptor activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in detection of chemical stimulus involved in sensory perception of bitter taste	IBA Inferred from Biological aspect of Ancestor more info
involved_in detection of chemical stimulus involved in sensory perception of bitter taste	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within detection of chemical stimulus involved in sensory perception of bitter taste	TAS Traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum	ISO Inferred from Sequence Orthology more info
located_in external side of plasma membrane	IEA Inferred from Electronic Annotation more info
located_in external side of plasma membrane	ISO Inferred from Sequence Orthology more info
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in trans-Golgi network	IEA Inferred from Electronic Annotation more info
located_in trans-Golgi network	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: taste receptor type 2 member 16

Names: candidate taste receptor mt2r40

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.