Slc27a3 solute carrier family 27 member 3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Slc27a3provided by RGD
Official Full Name: solute carrier family 27 member 3provided by RGD
Primary source: RGD:1310605
See related: EnsemblRapid:ENSRNOG00000015421 AllianceGenome:RGD:1310605
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable fatty-acyl-CoA synthase activity; long-chain fatty acid-CoA ligase activity; and very long-chain fatty acid-CoA ligase activity. Predicted to be involved in fatty acid transport and long-chain fatty acid metabolic process. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane; mitochondrion; and plasma membrane. Orthologous to human SLC27A3 (solute carrier family 27 member 3). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Adrenal (RPKM 308.7), Testes (RPKM 71.8) and 5 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 2q34

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	2	NC_086020.1 (178150835..178155503, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	2	NC_051337.1 (175853241..175857909, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	2	NC_005101.4 (189760747..189765415, complement)

Chromosome 2 - NC_086020.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH133053 (e-PCR)
- UniSTS:216336

RH139860 (e-PCR)
- UniSTS:221944

UniSTS:234745 (e-PCR)
- UniSTS:234745

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables fatty-acyl-CoA synthase activity	ISO Inferred from Sequence Orthology more info
enables long-chain fatty acid-CoA ligase activity	IBA Inferred from Biological aspect of Ancestor more info
enables long-chain fatty acid-CoA ligase activity	ISO Inferred from Sequence Orthology more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables very long-chain fatty acid-CoA ligase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
NOT acts_upstream_of_or_within fatty acid transport	ISO Inferred from Sequence Orthology more info
involved_in fatty acid transport	ISO Inferred from Sequence Orthology more info
involved_in long-chain fatty acid metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in long-chain fatty acid metabolic process	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	ISO Inferred from Sequence Orthology more info
is_active_in endoplasmic reticulum membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: long-chain fatty acid transport protein 3

Names: solute carrier family 27 (fatty acid transporter), member 3

NP_001099909.1

EC 6.2.1.15

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001106439.1 → NP_001099909.1 long-chain fatty acid transport protein 3 precursor

See identical proteins and their annotated locations for NP_001099909.1

Status: PROVISIONAL

Source sequence(s)

CH473976

UniProtKB/TrEMBL

A6J6L8, D3ZJA9

Related

ENSRNOP00000020815.4, ENSRNOT00000020815.7

Conserved Domains (2) summary

PRK08279
Location:60 → 666

PRK08279; long-chain-acyl-CoA synthetase; Validated

cl17068
Location:91 → 657

AFD_class_I; Adenylate forming domain, Class I superfamily