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    Zfp773 zinc finger protein 773 [ Mus musculus (house mouse) ]

    Gene ID: 76373, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp773provided by MGI
    Official Full Name
    zinc finger protein 773provided by MGI
    Primary source
    MGI:MGI:1923623
    See related
    Ensembl:ENSMUSG00000063535 AllianceGenome:MGI:1923623
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2810409K11Rik
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Is expressed in several structures, including central nervous system; dorsal root ganglion; genitourinary system; and sensory organ. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in CNS E14 (RPKM 2.0), whole brain E14.5 (RPKM 1.7) and 8 other tissues See more
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    Genomic context

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    See Zfp773 in Genome Data Viewer
    Location:
    7 A1; 7 4.14 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (7133677..7139754, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (7130678..7136755, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 954 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E2222 Neighboring gene zinc finger protein 954 Neighboring gene STARR-seq mESC enhancer starr_18003 Neighboring gene STARR-seq mESC enhancer starr_18004 Neighboring gene STARR-seq mESC enhancer starr_18005 Neighboring gene vomeronasal 2, receptor, pseudogene 35 Neighboring gene zinc finger protein 418

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract. Wiese CB, et al. Front Neurosci, 2012. PMID 22988430, Free PMC Article
    2. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article
    3. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
    4. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
    5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC76373
    Names
    zinc finger protein LOC76373

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029584.1 → NP_083860.1  uncharacterized protein LOC76373

      See identical proteins and their annotated locations for NP_083860.1

      Status: VALIDATED

      Source sequence(s)
      AK031040, BC117497
      Consensus CDS
      CCDS51992.1
      UniProtKB/TrEMBL
      Q9CZ29
      Related
      ENSMUSP00000032622.8, ENSMUST00000032622.9
      Conserved Domains (4) summary
      COG5048
      Location:180 → 418
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:243 → 263
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:75 → 114
      KRAB; KRAB box
      pfam13465
      Location:283 → 308
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      7133677..7139754 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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