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    Otud1 OTU domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 71198, updated on 9-Dec-2024

    Summary

    Official Symbol
    Otud1provided by MGI
    Official Full Name
    OTU domain containing 1provided by MGI
    Primary source
    MGI:MGI:1918448
    See related
    Ensembl:ENSMUSG00000043415 AllianceGenome:MGI:1918448
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4933428L19Rik
    Summary
    Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in protein K63-linked deubiquitination. Is expressed in embryo. Orthologous to human OTUD1 (OTU deubiquitinase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See Otud1 in Genome Data Viewer
    Location:
    2 A3; 2 13.78 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (19662542..19666090)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (19657731..19661279)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 39764 Neighboring gene STARR-seq mESC enhancer starr_03829 Neighboring gene STARR-seq mESC enhancer starr_03830 Neighboring gene STARR-positive B cell enhancer ABC_E5895 Neighboring gene STARR-positive B cell enhancer ABC_E5896 Neighboring gene predicted gene 13348 Neighboring gene STARR-positive B cell enhancer ABC_E4416 Neighboring gene STARR-positive B cell enhancer ABC_E7795 Neighboring gene predicted gene 3230 Neighboring gene GTPase activating protein (SH3 domain) binding protein 2 pseudogene Neighboring gene predicted gene, 24670

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables cysteine-type deubiquitinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables cysteine-type deubiquitinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in protein K63-linked deubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein K63-linked deubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     

    General protein information

    Preferred Names
    OTU domain-containing protein 1
    Names
    likely ortholog of H. sapiens OTU domain containing 1 (OTUD1)
    NP_081991.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027715.2NP_081991.1  OTU domain-containing protein 1

      See identical proteins and their annotated locations for NP_081991.1

      Status: VALIDATED

      Source sequence(s)
      AL928877
      Consensus CDS
      CCDS50508.1
      UniProtKB/Swiss-Prot
      A2ATK4, Q9CUB6
      Related
      ENSMUSP00000100617.3, ENSMUST00000052168.6
      Conserved Domains (1) summary
      pfam02338
      Location:288405
      OTU; OTU-like cysteine protease

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      19662542..19666090
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)