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    3110009E18Rik RIKEN cDNA 3110009E18 gene [ Mus musculus (house mouse) ]

    Gene ID: 73103, updated on 9-Dec-2024

    Summary

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    Official Symbol
    3110009E18Rikprovided by MGI
    Official Full Name
    RIKEN cDNA 3110009E18 geneprovided by MGI
    Primary source
    MGI:MGI:1920353
    See related
    Ensembl:ENSMUSG00000026388 AllianceGenome:MGI:1920353
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Orthologous to human C2orf76 (chromosome 2 open reading frame 76). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in liver adult (RPKM 17.5), CNS E14 (RPKM 2.7) and 1 other tissue See more
    Orthologs
    human all
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    Genomic context

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    See 3110009E18Rik in Genome Data Viewer
    Location:
    1 E2.3; 1 52.66 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (120047763..120115920)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (120121082..120188190)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E10029 Neighboring gene predicted gene, 41937 Neighboring gene predicted gene, 41938 Neighboring gene STARR-positive B cell enhancer ABC_E4342 Neighboring gene diazepam binding inhibitor Neighboring gene STARR-positive B cell enhancer mm9_chr1:122050580-122050881 Neighboring gene STARR-positive B cell enhancer mm9_chr1:122093817-122094118 Neighboring gene STARR-seq mESC enhancer starr_02054 Neighboring gene STEAP family member 3 Neighboring gene STARR-seq mESC enhancer starr_02055 Neighboring gene predicted gene, 53581 Neighboring gene STARR-seq mESC enhancer starr_02056 Neighboring gene complement component 1, q subcomponent-like 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette. Taniwaki T, et al. Dev Growth Differ, 2005 Apr. PMID 15840001
    2. Exchangeable gene trap using the Cre/mutated lox system. Araki K, et al. Cell Mol Biol (Noisy-le-grand), 1999 Jul. PMID 10512203
    3. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
    4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    UPF0538 protein C2orf76 homolog

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001172074.1 → NP_001165545.1  UPF0538 protein C2orf76 homolog isoform 2

      See identical proteins and their annotated locations for NP_001165545.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) skips an alternate exon in the 3' coding region resulting in a frameshift, compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AK014026, BC028767
      Consensus CDS
      CCDS48342.1
      UniProtKB/Swiss-Prot
      Q9CRW3
      Related
      ENSMUSP00000027637.7, ENSMUST00000027637.13
      Conserved Domains (1) summary
      pfam10209
      Location:8 → 78
      DUF2340; Uncharacterized conserved protein (DUF2340)

    2. NM_028439.2 → NP_082715.1  UPF0538 protein C2orf76 homolog isoform 1

      See identical proteins and their annotated locations for NP_082715.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AK014026, BC028767
      Consensus CDS
      CCDS15232.1
      UniProtKB/Swiss-Prot
      Q8K163, Q9CRW3
      Related
      ENSMUSP00000108263.3, ENSMUST00000112644.9
      Conserved Domains (1) summary
      pfam10209
      Location:8 → 122
      DUF2340; Uncharacterized conserved protein (DUF2340)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      120047763..120115920
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030243151.2 → XP_030099011.1  UPF0538 protein C2orf76 homolog isoform X5

      Related
      ENSMUSP00000053335.9, ENSMUST00000056038.15
      Conserved Domains (1) summary
      pfam10209
      Location:8 → 78
      DUF2340; Uncharacterized conserved protein (DUF2340)

    2. XM_006529893.4 → XP_006529956.1  UPF0538 protein C2orf76 homolog isoform X2

      Conserved Domains (1) summary
      pfam10209
      Location:8 → 98
      DUF2340; Uncharacterized conserved protein (DUF2340)

    3. XM_017312453.3 → XP_017167942.1  UPF0538 protein C2orf76 homolog isoform X4

      Conserved Domains (1) summary
      pfam10209
      Location:14 → 84
      DUF2340; Uncharacterized conserved protein (DUF2340)

    4. XM_017312451.3 → XP_017167940.1  UPF0538 protein C2orf76 homolog isoform X1

      Conserved Domains (1) summary
      pfam10209
      Location:14 → 104
      DUF2340; Uncharacterized conserved protein (DUF2340)

    5. XM_017312452.3 → XP_017167941.1  UPF0538 protein C2orf76 homolog isoform X3

      Conserved Domains (1) summary
      pfam10209
      Location:14 → 132
      DUF2340; Uncharacterized conserved protein (DUF2340)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9CRW3.2 GenPept UniProtKB/Swiss-Prot:Q9CRW3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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