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    Ppp1r26 protein phosphatase 1, regulatory subunit 26 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 685398, updated on 9-Dec-2024

    Summary

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    Symbol
    Ppp1r26provided by RGD
    Full Name
    protein phosphatase 1, regulatory subunit 26provided by RGD
    Primary source
    RGD:1595050
    See related
    EnsemblRapid:ENSRNOG00000027193 AllianceGenome:RGD:1595050
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    AABR07051376.1
    Summary
    Predicted to enable protein phosphatase inhibitor activity. Predicted to be involved in negative regulation of phosphatase activity. Orthologous to human PPP1R26 (protein phosphatase 1 regulatory subunit 26). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 112.5), Brain (RPKM 77.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ppp1r26 in Genome Data Viewer
    Location:
    3p12
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (32179686..32188069)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (11781504..11790076)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (7032118..7040615)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene Microtubule-associated proteins 1A/1B light chain 3B-like Neighboring gene uncharacterized LOC134486352 Neighboring gene piercer of microtubule wall 1 Neighboring gene mitochondrial ribosomal protein S2 Neighboring gene globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Docking motif-guided mapping of the interactome of protein phosphatase-1. Hendrickx A, et al. Chem Biol, 2009 Apr 24. PMID 19389623
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables protein phosphatase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein phosphatase 1 regulatory subunit 26
    Names
    rCG45515-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427208.1 → NP_001414137.1  protein phosphatase 1 regulatory subunit 26

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      A6JTN0, D3ZPW4

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      32179686..32188069
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039106150.2 → XP_038962078.1  protein phosphatase 1 regulatory subunit 26 isoform X1

      UniProtKB/TrEMBL
      A6JTN0, D3ZPW4
      Conserved Domains (1) summary
      pfam15740
      Location:1 → 808
      PPP1R26_N; Protein phosphatase 1 regulatory subunit 26 N-terminus

    2. XM_039106149.2 → XP_038962077.1  protein phosphatase 1 regulatory subunit 26 isoform X1

      UniProtKB/TrEMBL
      A6JTN0, D3ZPW4
      Related
      ENSRNOP00000037924.5, ENSRNOT00000036601.6
      Conserved Domains (1) summary
      pfam15740
      Location:1 → 808
      PPP1R26_N; Protein phosphatase 1 regulatory subunit 26 N-terminus

    3. XM_039106146.2 → XP_038962074.1  protein phosphatase 1 regulatory subunit 26 isoform X1

      UniProtKB/TrEMBL
      A6JTN0, D3ZPW4
      Related
      ENSRNOP00000078859.1, ENSRNOT00000102380.2
      Conserved Domains (1) summary
      pfam15740
      Location:1 → 808
      PPP1R26_N; Protein phosphatase 1 regulatory subunit 26 N-terminus

    4. XM_063284559.1 → XP_063140629.1  protein phosphatase 1 regulatory subunit 26 isoform X1

      UniProtKB/TrEMBL
      A6JTN0, D3ZPW4
    Nucleotide Protein Strain
    Heading Accession and Version

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