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    Dpy19l1 dpy-19 like C-mannosyltransferase 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 315496, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Dpy19l1provided by RGD
    Official Full Name
    dpy-19 like C-mannosyltransferase 1provided by RGD
    Primary source
    RGD:1305822
    See related
    EnsemblRapid:ENSRNOG00000026589 AllianceGenome:RGD:1305822
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1305822
    Summary
    Predicted to enable mannosyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human DPY19L1 (dpy-19 like C-mannosyltransferase 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Brain (RPKM 181.0), Spleen (RPKM 139.8) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Dpy19l1 in Genome Data Viewer
    Location:
    8q13
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (31209025..31297485, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (22933163..23021461, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (25582938..25669394, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene S100 calcium binding protein A11, pseudogene 5 Neighboring gene neuropeptide S receptor 1 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene dpy-19 like 2 Neighboring gene T-box transcription factor 20

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Defining the membrane proteome of NK cells. Ghosh D, et al. J Mass Spectrom, 2010 Jan. PMID 19946888
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mannosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein C-mannosyl-transferase DPY19L1
    Names
    dpy-19 like 1
    dpy-19-like protein 1
    probable C-mannosyltransferase DPY19L1
    protein dpy-19 homolog 1
    NP_001178720.1
    XP_038937290.1
    XP_038937291.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191791.2 → NP_001178720.1  protein C-mannosyl-transferase DPY19L1

      See identical proteins and their annotated locations for NP_001178720.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/Swiss-Prot
      D4AD75
      UniProtKB/TrEMBL
      A0A8I6G3Y6
      Related
      ENSRNOP00000033222.4, ENSRNOT00000036738.8
      Conserved Domains (1) summary
      pfam10034
      Location:105 → 743
      Dpy19; Q-cell neuroblast polarisation

    2. NM_001429803.1 → NP_001416732.1  protein C-mannosyl-transferase DPY19L1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/Swiss-Prot
      D4AD75

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      31209025..31297485 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039081362.2 → XP_038937290.1  protein C-mannosyl-transferase DPY19L1 isoform X1

      Conserved Domains (1) summary
      pfam10034
      Location:105 → 743
      Dpy19; Q-cell neuroblast polarisation

    2. XM_039081363.2 → XP_038937291.1  protein C-mannosyl-transferase DPY19L1 isoform X2

      Conserved Domains (1) summary
      pfam10034
      Location:1 → 587
      Dpy19; Q-cell neuroblast polarisation
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    D4AD75.1 GenPept UniProtKB/Swiss-Prot:D4AD75

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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